Phthalates are a huge class of chemicals with a wide spectrum of industrial uses, from the
manufacture of plastics to food contact applications, children's toys, and medical devices …

Individuals suffering from severe viral respiratory tract infections have recently emerged as
“at risk” groups for developing invasive fungal infections. Influenza virus is one of the most …

INTRODUCTION Dendritic cells (DC) are professional antigen-presenting cells that
orchestrate immune responses. The human DC population comprises multiple subsets …

Vaccines containing novel adjuvant formulations are increasingly reaching advanced
development and licensing stages, providing new tools to fill previously unmet clinical …

Influenza remains one of the major public health concerns because it causes annual
epidemics and can potentially instigate a global pandemic. Numerous countermeasures …

A major goal of systems biology is the development of models that accurately predict
responses to perturbation. Constructing such models requires the collection of dense …

Interferons (IFNs) are critical for protection from viral infection, but the pathways linking virus
recognition to IFN induction remain poorly understood. Plasmacytoid dendritic cells produce …

Human and mouse plasmacytoid dendritic cells have been shown to correspond to a
specialized cell population that produces large amounts of type I interferons in response to …

Psoriasis is one of the most common T cell–mediated autoimmune diseases in humans.
Although a role for the innate immune system in driving the autoimmune T cell cascade has …

Dendritic cells (DCs) initiate and control immune responses. Plasmacytoid DCs (pDCs)
represent a unique DC subset able to promptly release large amounts of type I interferon …