Phosphorylated tau in Alzheimer's disease and other tauopathies
Alzheimer's disease (AD) is the leading cause of dementia in elderly people. Amyloid beta
(Aβ) deposits and neurofibrillary tangles are the major pathological features in an …
(Aβ) deposits and neurofibrillary tangles are the major pathological features in an …
Role of tau protein in Alzheimer's disease: The prime pathological player
Alzheimer's disease (AD) is a prevalently found tauopathy characterized by memory loss
and cognitive insufficiency. AD is an age-related neurodegenerative disease with two major …
and cognitive insufficiency. AD is an age-related neurodegenerative disease with two major …
Alzheimer's disease
HW Querfurth, FM LaFerla - New England Journal of Medicine, 2010 - Mass Medical Soc
This review of Alzheimer's disease assembles a variety of findings relevant to the
mechanism of the disease and ties them together using the current understanding of the …
mechanism of the disease and ties them together using the current understanding of the …
Diabetes mellitus and Alzheimer's disease: GSK-3β as a potential link
Y Zhang, N Huang, F Yan, H Jin, S Zhou, J Shi… - Behavioural brain …, 2018 - Elsevier
It is well known that Alzheimer's disease (AD) is closely related to diabetes mellitus (DM),
and AD is also regarded as Type 3 diabetes (T3D). However, the exact link between AD and …
and AD is also regarded as Type 3 diabetes (T3D). However, the exact link between AD and …
Inflammasomes in neuroinflammation and changes in brain function: a focused review
Recent literature has pointed to the existence of inflammasome-mediated inflammatory
pathways in central nervous system (CNS) disorders and associated changes in behavior …
pathways in central nervous system (CNS) disorders and associated changes in behavior …
Post-translational modifications of tau protein: implications for Alzheimer's disease
L Martin, X Latypova, F Terro - Neurochemistry international, 2011 - Elsevier
Alzheimer's disease (AD) belongs to a group of neurodegenerative diseases collectively
designated as “tauopathies”, because they are characterized by the aggregation of …
designated as “tauopathies”, because they are characterized by the aggregation of …
[HTML][HTML] Alzheimer disease
RJ Castellani, RK Rolston, MA Smith - Disease-a-month: DM, 2010 - ncbi.nlm.nih.gov
In 1907, Alois Alzheimer described the case of a 51 year old woman who presented with a
relatively rapidly deteriorating memory along with psychiatric disturbances. She died four …
relatively rapidly deteriorating memory along with psychiatric disturbances. She died four …
Advancements in the development of multi-target directed ligands for the treatment of Alzheimer's disease
Alzheimer's disease (AD) is a multifactorial irreversible neurological disorder which results
in cognitive impairment, loss of cholinergic neurons in synapses of the basal forebrain and …
in cognitive impairment, loss of cholinergic neurons in synapses of the basal forebrain and …
Oxidative stress in Alzheimer disease: a possibility for prevention
Oxidative stress is at the forefront of Alzheimer disease (AD) research. While its implications
in the characteristic neurodegeneration of AD are vast, the most important aspect is that it …
in the characteristic neurodegeneration of AD are vast, the most important aspect is that it …
Involvement of oxidative stress in Alzheimer disease
A Nunomura, RJ Castellani, X Zhu… - … of neuropathology & …, 2006 - academic.oup.com
Genetic and lifestyle-related risk factors for Alzheimer disease (AD) are associated with an
increase in oxidative stress, suggesting that oxidative stress is involved at an early stage of …
increase in oxidative stress, suggesting that oxidative stress is involved at an early stage of …