There has been an increasing demand for the development of nanocarriers targeting
multiple diseases with a broad range of properties. Due to their tiny size, giant surface area …

This review summarizes the methods used to study real‐time (37° C) drug release from
nanoparticulate drug delivery systems and establish an IVIVC. Since no compendial …

Drug absorption from the gastrointestinal (GI) tract is a highly complex process dependent
upon numerous factors including the physicochemical properties of the drug, characteristics …

Nanoparticulate systems have emerged as prevalent drug delivery systems over the past
few decades. These delivery systems (such as liposomes, emulsions, nanocrystals, and …

After decades of research, nanotechnology has been used in a broad array of biomedical
products including medical devices, drug products, drug substances, and pharmaceutical …

Lipid-based formulations (LBFs) have demonstrated a great potential in enhancing the oral
absorption of poorly water-soluble drugs. However, construction of in vitro and in vivo …

Introduction: For poorly soluble compounds, a good bioavailability is typically needed to
assess the therapeutic index and the suitability of the compound for technical development …

The objectives of this study were to characterise three prototype fenofibrate lipid-based
formulations using a range of in vitro tests with differing levels of complexity and to assess …

Nanocrystal technology has emerged as a valuable tool for facilitating the delivery of poorly
water-soluble active pharmaceutical ingredients (APIs) and enhancing API bioavailability …

The aim of the present series of experiments was to improve the solubility and dissolution/
precipitation behaviour of a poorly soluble, weakly basic drug, using itraconazole as a case …