Voltage sensors of a Na+ channel dissociate from the pore domain and form inter-channel dimers in the resting state

A Sumino, T Sumikama, M Shibata, K Irie - Nature Communications, 2023 - nature.com
Understanding voltage-gated sodium (Nav) channels is significant since they generate
action potential. Nav channels consist of a pore domain (PD) and a voltage sensor domain …

A native prokaryotic voltage-dependent calcium channel with a novel selectivity filter sequence

T Shimomura, Y Yonekawa, H Nagura, M Tateyama… - Elife, 2020 - elifesciences.org
Voltage-dependent Ca2+ channels (Cavs) are indispensable for coupling action potentials
with Ca2+ signaling in living organisms. The structure of Cavs is similar to that of voltage …

Arrangement and mobility of the voltage sensor domain in prokaryotic voltage-gated sodium channels

T Shimomura, K Irie, H Nagura, T Imai… - Journal of Biological …, 2011 - ASBMB
Prokaryotic voltage-gated sodium channels (Na V s) form homotetramers with each subunit
contributing six transmembrane α-helices (S1–S6). Helices S5 and S6 form the ion …

Structural physiology based on electron crystallography

Y Fujiyoshi - Protein Science, 2011 - Wiley Online Library
There are many questions in brain science, which are extremely interesting but very difficult
to answer. For example, how do education and other experiences during human …

[PDF][PDF] Interchannel dimerization of the dissociated voltage-sensor domains of voltage-gated Na+ channels in the resting state

A Sumino, T Sumikama, M Shibata, K Irie - 2023 - researchgate.net
Understanding voltage-gated sodium (Nav) channels is signi cant since they generate
action potential. Nav channels consist of a pore domain (PD) and a voltage-sensor domain …

RETRACTED: Voltage sensor ring in a native structure of a membrane-embedded potassium channel

L Shi, H Zheng, H Zheng, BA Borkowski, D Shi… - Proceedings of the …, 2013 - pnas.org
Voltage-gated ion channels support electrochemical activity in cells and are largely
responsible for information flow throughout the nervous systems. The voltage sensor …

[PDF][PDF] A native prokaryotic voltage-dependent calcium channel with a novel selectivity filter

T Shimomura, Y Yonekawa, H Nagura, M Tateyama… - channels - scholar.archive.org
Abstract Voltage-dependent Ca 2+ channels (Cavs) are indispensable for coupling action
potentials with Ca 2+ signaling in living organisms. The structure of Cavs is similar to that of …

Retraction for Shi et al.," Voltage sensor ring in a native structure of a membrane-embedded potassium channel".

L Shi, H Zheng, BA Borkowski, D Shi… - Proceedings of the …, 2013 - europepmc.org
The authors wish to note the following:“The contrast of our final projection map was inverted,
so that we interpreted the background density rather than the actual protein density in terms …