The role of APOBECs in viral replication

WK Xu, H Byun, JP Dudley - Microorganisms, 2020 - mdpi.com
Apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like (APOBEC) proteins are a
diverse and evolutionarily conserved family of cytidine deaminases that provide a variety of …

Regulation of viral restriction by post-translational modifications

C Chamontin, G Bossis, S Nisole, NJ Arhel, G Maarifi - Viruses, 2021 - mdpi.com
Intrinsic immunity is orchestrated by a wide range of host cellular proteins called restriction
factors. They have the capacity to interfere with viral replication, and most of them are tightly …

USP49 potently stabilizes APOBEC3G protein by removing ubiquitin and inhibits HIV-1 replication

T Pan, Z Song, L Wu, G Liu, X Ma, Z Peng, M Zhou… - Elife, 2019 - elifesciences.org
The antiviral activity of host factor apolipoprotein B mRNA editing enzyme catalytic
polypeptide-like 3G (APOBEC3G, A3G) and its degradation mediated by human …

Polymorphisms in human APOBEC3H differentially regulate ubiquitination and antiviral activity

NM Chesarino, M Emerman - Viruses, 2020 - mdpi.com
The APOBEC3 family of cytidine deaminases are an important part of the host innate
immune defense against endogenous retroelements and retroviruses like Human …

Ubiquitination and SUMOylation in HIV infection: Friends and foes

M Colomer-Lluch, S Castro-Gonzalez… - Current issues in …, 2020 - mdpi.com
As intracellular parasites, viruses hijack the cellular machinery to facilitate their replication
and spread. This includes favouring the expression of their viral genes over host genes …

Design, synthesis and biological evaluation of indole derivatives as Vif inhibitors

C Pu, RH Luo, M Zhang, X Hou, G Yan, J Luo… - Bioorganic & medicinal …, 2017 - Elsevier
The crystal structure of viral infectivity factor (Vif) was reported recently, which makes it
possible to design new inhibitors against Vif by structure-based drug design. Through …

HIV Restriction Factor APOBEC3G and Prospects for Its Use in Gene Therapy for HIV

AS Tikhonov, RR Mintaev, DV Glazkova… - Molecular Biology, 2022 - Springer
The mechanisms for the protection of the human body from viral or bacterial agents are
extremely diverse. In one such mechanism, an important role belongs to the cytidine …

[图书][B] Host-Viral Interactions and Innate Immune Evasion of SARS-CoV-2 Nsp14 and HIV-1 Vif

VL Lam - 2023 - search.proquest.com
Viruses are obligate intracellular parasites and must rely on interactions with host proteins
and machinery to produce progeny. Over time, hosts have developed innate immune …

[PDF][PDF] Eine vergleichende molekulare Analyse viraler DDB1-bindender Proteine im Kontext ihrer immunevasiven Eigenschaften

CD Landsberg - 2018 - scholar.archive.org
Viren sind obligat intrazelluläre Parasiten, die keinen eigenen Stoffwechsel besitzen. Sie
werden deshalb von einigen Autoren nicht als autarke Lebewesen eingestuft. Sie können …

[引用][C] Down to the Molecular Mechanisms of Host-Pathogen Interactions.

H Hodak - Journal of Molecular Biology, 2016 - europepmc.org
Down to the Molecular Mechanisms of Host-Pathogen Interactions. - Abstract - Europe PMC
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