In the last decades, the increased number of immunocompromised patients has led to the
emergence of many forms of fungal infections. Furthermore, there are a restricted arsenal of …

Abstract Yes-associated protein (YAP), the central mediator of Hippo pathway, not only
regulates a diversity of cellular processes during development but also plays a pivotal role in …

Ethnopharmacological relevance The plants in the genus Carpesium, which grow naturally
in Asia and Europe, have long been used in traditional Chinese, Korean and Japanese …

Complete synthetic, structural, and biomedical studies of two Pd complexes as well as Au
and Ag complexes of 1-benzyl-3-tert-butylimidazol-2-ylidene are reported. Specifically, trans …

Purpose The aim of the present study was to blend liquid lipids with solid lipids to
encapsulate curcumin in solid lipid nanoparticles (SLNs), thereby improving the …

To test the ability of nanoparticle formulations to overcome P-glycoprotein (P-gp)–mediated
multidrug resistance, several different doxorubicin and paclitaxel-loaded lipid nanoparticles …

The sulforhodamine B (SRB) assay was developed by Skehan and colleagues to measure
drug-induced cytotoxicity and cell proliferation for large-scale drug-screening applications …

Cinnamic acids have been identified as interesting compounds with antioxidant, anti-
inflammatory and cytotoxic properties. In the present study, simple cinnamic acids were …

Inconsistencies in the half-maximal (50%) inhibitory concentration (IC 50) data for anticancer
chemotherapeutic agents have yielded irreproducible experimental results and thus …

The synthesis is reported of a group of 3, 6, 9-trisubstituted acridine compounds as telomeric
quadruplex-stabilizing ligands with systematic variations at the 3-, 6-, and 9-positions. A new …