Anomalous transport in the crowded world of biological cells
F Höfling, T Franosch - Reports on Progress in Physics, 2013 - iopscience.iop.org
A ubiquitous observation in cell biology is that the diffusive motion of macromolecules and
organelles is anomalous, and a description simply based on the conventional diffusion …
organelles is anomalous, and a description simply based on the conventional diffusion …
Dynamic organizing principles of the plasma membrane that regulate signal transduction: commemorating the fortieth anniversary of Singer and Nicolson's fluid …
A Kusumi, TK Fujiwara, R Chadda, M Xie… - Annual review of cell …, 2012 - annualreviews.org
The recent rapid accumulation of knowledge on the dynamics and structure of the plasma
membrane has prompted major modifications of the textbook fluid-mosaic model. However …
membrane has prompted major modifications of the textbook fluid-mosaic model. However …
Hierarchical mesoscale domain organization of the plasma membrane
Based on recent single-molecule imaging results in the living cell plasma membrane, we
propose a hierarchical architecture of three-tiered mesoscale (2–300nm) domains to …
propose a hierarchical architecture of three-tiered mesoscale (2–300nm) domains to …
Nonergodicity mimics inhomogeneity in single particle tracking
A Lubelski, IM Sokolov, J Klafter - Physical review letters, 2008 - APS
Most statistical theories of anomalous diffusion rely on ensemble-averaged quantities such
as the mean squared displacement. Single molecule tracking measurements require …
as the mean squared displacement. Single molecule tracking measurements require …
Advances in image correlation spectroscopy: measuring number densities, aggregation states, and dynamics of fluorescently labeled macromolecules in cells
DL Kolin, PW Wiseman - Cell biochemistry and biophysics, 2007 - Springer
A brief historical outline of fluorescence fluctuation correlation techniques is presented,
followed by an in-depth review of the theory and development of image correlation …
followed by an in-depth review of the theory and development of image correlation …
[HTML][HTML] Guidelines for the fitting of anomalous diffusion mean square displacement graphs from single particle tracking experiments
Single particle tracking is an essential tool in the study of complex systems and biophysics
and it is commonly analyzed by the time-averaged mean square displacement (MSD) of the …
and it is commonly analyzed by the time-averaged mean square displacement (MSD) of the …
[HTML][HTML] Diffusion anisotropy in collagen gels and tumors: the effect of fiber network orientation
The interstitial matrix is comprised of cross-linked collagen fibers, generally arranged in
nonisotropic orientations. Spatial alignment of matrix components within the tissue can affect …
nonisotropic orientations. Spatial alignment of matrix components within the tissue can affect …
[HTML][HTML] Hierarchical organization of the plasma membrane: investigations by single-molecule tracking vs. fluorescence correlation spectroscopy
A Kusumi, YM Shirai, I Koyama-Honda, KGN Suzuki… - FEBS letters, 2010 - Elsevier
Single-molecule tracking and fluorescence correlation spectroscopy (FCS) applied to the
plasma membrane in living cells have allowed a number of unprecedented observations …
plasma membrane in living cells have allowed a number of unprecedented observations …
Tracking single molecules in the live cell plasma membrane—Do's and Don't's
S Wieser, GJ Schütz - Methods, 2008 - Elsevier
In recent years, the development of fast and highly sensitive microscopy has changed the
way of thinking of cell biologists: it became more and more important to study the structural …
way of thinking of cell biologists: it became more and more important to study the structural …
Membrane mechanisms for signal transduction: the coupling of the meso-scale raft domains to membrane-skeleton-induced compartments and dynamic protein …
A Kusumi, TK Fujiwara, N Morone, KJ Yoshida… - Seminars in cell & …, 2012 - Elsevier
Virtually all biological membranes on earth share the basic structure of a two-dimensional
liquid. Such universality and peculiarity are comparable to those of the double helical …
liquid. Such universality and peculiarity are comparable to those of the double helical …