Wild type genotypes (CYP2D6) and their allelic variants have been described in a sample of
a Peruvian mestizo population. The global allele frequency was 0.015 for CYP2D6* 3 and …

The polymorphic variants of CYP1A1 and the deletion of GSTM1 are present in the Peruvian
mestizo population. Wild type and mutated genotypes (WT/* 2A and* 2A/* 2A) were …

Carbamazepine is a drug with a narrow therapeutic range that requires clinical monitoring,
since its toxic effects are not easily predictable, and the therapeutic level can vary. Our study …

Objetivos: Revisar e integrar la información sobre las interacciones farmacocinéticas de la
azitromicina que se prescriben en el tratamiento ambulatorio de la COVID-19 en el Perú, y …

Epilepsy is the most common neurological disorder with a worldwide incidence of 20% and
a treatment failure rate of 25–30%. The fluctuation in serum levels, efficacy and safety of …

Alleles in the VKORC1, CYP2C9, and CYP4F2 genes can influence Warfarin dose
requirement. We aimed to determine the frequency of the polymorphisms in these genes in …

This in vitro study evaluated the therapeutic equivalence of two multisource (generic)
formulations of 100-mg phenytoin as immediate-release tablets available in the Peruvian …

Introducción La fenitoína es usada con mucha frecuencia en nuestro medio, por lo que se
requiere hacer estudios de monitorización terapéutica, que contribuya a minimizar los …

In clinical practice, therapeutic drug monitoring (TDM) makes it possible to measure the
concentration of drugs in serum or saliva, the purpose of which is to reduce adverse effects …

In clinical practice, therapeutic drug monitoring (TDM) makes it possible to measure the
concentration of drugs in serum or saliva, the purpose of which is to reduce adverse effects …