Luminal nutrition is important for maintenance of gastrointestinal mucosal structure and
function. In particular, short chain fatty acids (SCFAs), metabolic products of anaerobic …

Butyrate is produced in the colon of mammals as a result of microbial fermentation of dietary
fiber, undigested starch, and proteins. Butyrate may be an important protective agent in …

1. Effects of short-chain fatty acids (SCFA) on epithelial proliferation of the intestine were
studied in ileally fistulated rats fed on an elemental diet. 2. The stimulatory effect of daily …

In recent years, the emphasis in drug development has been the design of new delivery
systems rather than new drugs. It is the aim of innovative pharmaceutical scientists to design …

BACKGROUND/AIMS Impaired colonocyte metabolism of butyrate has been implicated in
the aetiopathogenesis of ulcerative colitis. Colonocyte butyrate metabolism was investigated …

Fermentable dietary fiber components are known to stimulate colonic crypt proliferation. As
these compounds are rapidly degraded to short‐chain fatty acids (SCFAs) by the anaerobic …

Background—Fermentable dietary fibre has many effects on the gastrointestinal tract. One is
to alter epithelial crypt cell proliferation, especially in the colon. A discrepancy between …

Gastrointestinal cell proliferation plays an important role in the maintenance of the integrity
of the gastrointestinal system. The study of gastrointestinal proliferation kinetics allows a …

Two experiments were conducted with neonatal pigs to determine the effects of feeding
fructooligosaccharides on cecal and colonic microbiota, proliferation of cecal and colonic …

This book discusses the role of the large intestine in health and also common large intestine
diseases under the following headings: anatomy, bacteriology and function; carbohydrate …