Neurophysiological and computational principles of cortical rhythms in cognition

XJ Wang - Physiological reviews, 2010 - journals.physiology.org
Synchronous rhythms represent a core mechanism for sculpting temporal coordination of
neural activity in the brain-wide network. This review focuses on oscillations in the cerebral …

Neuronal dynamics and neuropsychiatric disorders: toward a translational paradigm for dysfunctional large-scale networks

PJ Uhlhaas, W Singer - Neuron, 2012 - cell.com
In recent years, numerous studies have tested the relevance of neural oscillations in
neuropsychiatric conditions, highlighting the potential role of changes in temporal …

NMDAR hypofunction animal models of schizophrenia

G Lee, Y Zhou - Frontiers in molecular neuroscience, 2019 - frontiersin.org
The N-methyl-d-aspartate receptor (NMDAR) hypofunction hypothesis has been proposed to
help understand the etiology and pathophysiology of schizophrenia. This hypothesis was …

Current findings and perspectives on aberrant neural oscillations in schizophrenia

Y Hirano, PJ Uhlhaas - Psychiatry and clinical neurosciences, 2021 - Wiley Online Library
There is now consistent evidence that neural oscillation at low‐and high‐frequencies
constitute an important aspect of the pathophysiology of schizophrenia. Specifically …

Oscillations and hippocampal–prefrontal synchrony

LL Colgin - Current opinion in neurobiology, 2011 - Elsevier
The hippocampus, a structure required for many types of memory, connects to the medial
prefrontal cortex, an area that helps direct neuronal information streams during intentional …

Oscillations and neuronal dynamics in schizophrenia: the search for basic symptoms and translational opportunities

PJ Uhlhaas, W Singer - Biological psychiatry, 2015 - Elsevier
A considerable body of work over the last 10 years combining noninvasive
electrophysiology (electroencephalography/magnetoencephalography) in patient …

Molecular evidence of N-methyl-D-aspartate receptor hypofunction in schizophrenia

CS Weickert, SJ Fung, VS Catts, PR Schofield… - Molecular …, 2013 - nature.com
Blockade of N-methyl-D-aspartate receptors (NMDARs) produces behavior in healthy
people that is similar to the psychotic symptoms and cognitive deficits of schizophrenia and …

Gamma synchrony: towards a translational biomarker for the treatment-resistant symptoms of schizophrenia

MJ Gandal, JC Edgar, K Klook, SJ Siegel - Neuropharmacology, 2012 - Elsevier
The lack of efficacy for antipsychotics with respect to negative symptoms and cognitive
deficits is a significant obstacle for the treatment of schizophrenia. Developing new drugs to …

The rhythm of memory: how breathing shapes memory function

DH Heck, R Kozma, LM Kay - Journal of neurophysiology, 2019 - journals.physiology.org
The mammalian olfactory bulb displays a prominent respiratory rhythm, which is linked to the
sniff cycle and is driven by sensory input from olfactory receptors in the nasal sensory …

Neuromodulation of hippocampal-prefrontal cortical synaptic plasticity and functional connectivity: implications for neuropsychiatric disorders

RN Ruggiero, MT Rossignoli, DB Marques… - Frontiers in cellular …, 2021 - frontiersin.org
The hippocampus-prefrontal cortex (HPC-PFC) pathway plays a fundamental role in
executive and emotional functions. Neurophysiological studies have begun to unveil the …