Approximately 70 human RNA-binding proteins (RBPs) contain a prion-like domain (PrLD).
PrLDs are low-complexity domains that possess a similar amino acid composition to prion …

Stress proteins (SPs) including heat-shock proteins (HSPs), RNA chaperones, and ER
associated stress proteins are molecular chaperones essential for cellular homeostasis. The …

Heterogeneous nuclear ribonucleoproteins (hnRNPs) are RNA‐binding proteins associated
with complex and diverse biological processes such as processing of heterogeneous …

Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) is a stress granule-associated
RNA-binding protein that plays a role in apoptosis and cellular stress recovery. HnRNP A1 is …

The full-length mRNAs of the human immunodeficiency virus type-1 (HIV-1), the human T-
cell lymphotropic virus type-1 (HTLV-1), and the mouse mammary tumor virus (MMTV) …

Efficient transcription of the HIV-1 genome is regulated by Tat, which recruits P-TEFb from
the 7SK small nuclear ribonucleoprotein (snRNP) and other nucleoplasmic complexes to …

Viruses are obligate parasites known to interact with a wide variety of host proteins at
different stages of infection. Current antiviral treatments target viral proteins and may be …

HIV-1 is able to express multiple protein types and isoforms from a single 9 kb mRNA
transcript. These proteins are also expressed at particular stages of viral development, and …

Abstract Lysyl oxidase-like 2 (LOXL2) is a member of the lysyl oxidase family and has the
ability to catalyze the cross-linking of extracellular matrix collagen and elastin. High …

Multiple sclerosis (MS) is a demyelinating, autoimmune disease of the central nervous
system. In recent years, it has become more evident that neurodegeneration, including …