It has been 50 years since Francis Fontan pioneered the operation that today bears his
name. Initially designed for patients with tricuspid atresia, this procedure is now offered for a …

Fontan-associated liver disease is a hepatic disorder arising from hemodynamic changes
and systemic venous congestion following Fontan surgery. The histological changes …

Background: The Fontan operation creates a total cavopulmonary connection, a circulation
in which the importance of pulmonary vascular resistance is magnified. Over time, this …

Although survival after the Fontan operation has improved, little is known about the burden
of major medical morbidities associated with the modern total cavopulmonary connection …

Background The influence of ventricular morphology on Fontan outcomes is controversial.
Objectives This study hypothesized that dysfunction of the single right ventricle (RV) and …

Congenital heart defects occur in 8 per 1000 live births, with anomalies ranging from minor
septal defects to major structural abnormalities of the great vessels or ventricles. Why focus …

Objectives: To determine the long-term (> 6 mo) functional status of PICU patients with
significant new functional morbidities at hospital discharge. Design: Longitudinal cohort …

Impaired exercise following Fontan is a surrogate of morbidity. Single-center longitudinal
data exist, but there is a lack of contemporary multi-center data. Ramp cycle ergometry was …

Fontan-palliated patients are at risk for the development of Fontan-associated liver disease
(FALD). In this study, we performed a detailed hemodynamic and hepatic assessment to …

Aim Fontan surgery is often the procedure of choice for patients with congenital single
effective ventricle. In the long term, elevated systemic venous pressure and chronic ischemia …