Selenium and selenoproteins: It's role in regulation of inflammation

S Hariharan, S Dharmaraj - Inflammopharmacology, 2020 - Springer
Selenium is an essential immunonutrient which holds the human's metabolic activity with its
chemical bonds. The organic forms of selenium naturally present in human body are …

Role for selenium in metabolic homeostasis and human reproduction

A Mojadadi, A Au, W Salah, P Witting, G Ahmad - Nutrients, 2021 - mdpi.com
Selenium (Se) is a micronutrient essential for life. Dietary intake of Se within the
physiological range is critical for human health and reproductive functions. Selenium levels …

Selenium metabolism and biosynthesis of selenoproteins in the human body

WB Minich - Biochemistry (Moscow), 2022 - Springer
As an essential trace element, selenium (Se) plays a tremendous role in the functioning of
the human organism being used for the biosynthesis of selenoproteins (proteins containing …

Selenium in thyroid disorders—essential knowledge for clinicians

KH Winther, MP Rayman, SJ Bonnema… - Nature Reviews …, 2020 - nature.com
In the 1990s, selenium was identified as a component of an enzyme that activates thyroid
hormone; since this discovery, the relevance of selenium to thyroid health has been widely …

The impact of selenium deficiency on cardiovascular function

BK Shimada, N Alfulaij, LA Seale - International journal of molecular …, 2021 - mdpi.com
Selenium (Se) is an essential trace element that is necessary for various metabolic
processes, including protection against oxidative stress, and proper cardiovascular function …

Glutathione peroxidases

R Brigelius-Flohé, M Maiorino - … et Biophysica Acta (BBA)-General Subjects, 2013 - Elsevier
BACKGROUND: With increasing evidence that hydroperoxides are not only toxic but rather
exert essential physiological functions, also hydroperoxide removing enzymes have to be re …

Selenium and human health

MP Rayman - The Lancet, 2012 - thelancet.com
Selenium is incorporated into selenoproteins that have a wide range of pleiotropic effects,
ranging from antioxidant and anti-inflammatory effects to the production of active thyroid …

Extracellular glutathione peroxidase GPx3 and its role in cancer

C Chang, BL Worley, R Phaëton, N Hempel - Cancers, 2020 - mdpi.com
Mammalian cells possess a multifaceted antioxidant enzyme system, which includes
superoxide dismutases, catalase, the peroxiredoxin/thioredoxin and the glutathione …

Multiple nutritional factors and thyroid disease, with particular reference to autoimmune thyroid disease

MP Rayman - Proceedings of the nutrition society, 2019 - cambridge.org
Hashimoto's thyroiditis (HT) and Graves' disease (GD) are examples of autoimmune thyroid
disease (AITD), the commonest autoimmune condition. Antibodies to thyroid peroxidase …

Selenium deficiency due to diet, pregnancy, severe illness, or covid-19—A preventable trigger for autoimmune disease

L Schomburg - International Journal of Molecular Sciences, 2021 - mdpi.com
The trace element selenium (Se) is an essential part of the human diet; moreover, increased
health risks have been observed with Se deficiency. A sufficiently high Se status is a …