Lipolysis: cellular mechanisms for lipid mobilization from fat stores
The perception that intracellular lipolysis is a straightforward process that releases fatty
acids from fat stores in adipose tissue to generate energy has experienced major revisions …
acids from fat stores in adipose tissue to generate energy has experienced major revisions …
Lipid droplets and cellular lipid metabolism
TC Walther, RV Farese Jr - Annual review of biochemistry, 2012 - annualreviews.org
Among organelles, lipid droplets (LDs) uniquely constitute a hydrophobic phase in the
aqueous environment of the cytosol. Their hydrophobic core of neutral lipids stores …
aqueous environment of the cytosol. Their hydrophobic core of neutral lipids stores …
FAT SIGNALS-lipases and lipolysis in lipid metabolism and signaling
R Zechner, R Zimmermann, TO Eichmann… - Cell metabolism, 2012 - cell.com
Lipolysis is defined as the catabolism of triacylglycerols stored in cellular lipid droplets.
Recent discoveries of essential lipolytic enzymes and characterization of numerous …
Recent discoveries of essential lipolytic enzymes and characterization of numerous …
Dissecting adipose tissue lipolysis: molecular regulation and implications for metabolic disease
Lipolysis is the process by which triglycerides (TGs) are hydrolyzed to free fatty acids (FFAs)
and glycerol. In adipocytes, this is achieved by sequential action of adipose TG lipase …
and glycerol. In adipocytes, this is achieved by sequential action of adipose TG lipase …
Regulation of adipocyte lipolysis
G Frühbeck, L Méndez-Giménez… - Nutrition research …, 2014 - cambridge.org
In adipocytes the hydrolysis of TAG to produce fatty acids and glycerol under fasting
conditions or times of elevated energy demands is tightly regulated by neuroendocrine …
conditions or times of elevated energy demands is tightly regulated by neuroendocrine …
[HTML][HTML] Lipolysis–a highly regulated multi-enzyme complex mediates the catabolism of cellular fat stores
A Lass, R Zimmermann, M Oberer, R Zechner - Progress in lipid research, 2011 - Elsevier
Lipolysis is the biochemical pathway responsible for the catabolism of triacylglycerol (TAG)
stored in cellular lipid droplets. The hydrolytic cleavage of TAG generates non-esterified fatty …
stored in cellular lipid droplets. The hydrolytic cleavage of TAG generates non-esterified fatty …
Lipolysis and lipid mobilization in human adipose tissue
M Lafontan, D Langin - Progress in lipid research, 2009 - Elsevier
Triacylglycerol (TAG) stored in adipose tissue (AT) can be rapidly mobilized by the hydrolytic
action of the three main lipases of the adipocyte. The non-esterified fatty acids (NEFA) …
action of the three main lipases of the adipocyte. The non-esterified fatty acids (NEFA) …
PAT proteins, an ancient family of lipid droplet proteins that regulate cellular lipid stores
The PAT family of lipid droplet proteins includes 5 members in mammals: perilipin, adipose
differentiation-related protein (ADRP), tail-interacting protein of 47 kDa (TIP47), S3–12, and …
differentiation-related protein (ADRP), tail-interacting protein of 47 kDa (TIP47), S3–12, and …
Recent progress in phospholipase A2 research: from cells to animals to humans
M Murakami, Y Taketomi, Y Miki, H Sato… - Progress in lipid …, 2011 - Elsevier
Mammalian genomes encode genes for more than 30 phospholipase A2s (PLA2s) or
related enzymes, which are subdivided into several classes including low-molecular-weight …
related enzymes, which are subdivided into several classes including low-molecular-weight …
Arf1/COPI machinery acts directly on lipid droplets and enables their connection to the ER for protein targeting
F Wilfling, AR Thiam, MJ Olarte, J Wang, R Beck… - elife, 2014 - elifesciences.org
Lipid droplets (LDs) are ubiquitous organelles that store neutral lipids, such as
triacylglycerol (TG), as reservoirs of metabolic energy and membrane precursors. The …
triacylglycerol (TG), as reservoirs of metabolic energy and membrane precursors. The …