The physicochemical nature of DNA allows the assembly of highly predictable structures via
several fabrication strategies, which have been applied to make breakthroughs in various …

Various binding modes of tunable metal organic frameworks (MOFs) and functional
DNAzymes (Dzs) synergistically catalyze the emergence of abundant functional …

Systemic immune monitoring is a crucial clinical tool for disease early diagnosis, prognosis
and treatment planning by quantitative analysis of immune cells. However, conventional …

Molecular profiling of tumor-derived extracellular vesicles (tEVs) holds great promise for non-
invasive cancer diagnosis. However, sensitive and accurate identification of tEVs is …

Isothermal nucleic acid amplification techniques have emerged as an important diagnostic
tool for clinical applications and food safety inspection. Rolling circle amplification (RCA) is …

With the continuous development of DNA nanotechnology, various spatial DNA structures
and assembly techniques emerge. Hybridization chain reaction (HCR) is a typical example …

A novel self-powered biosensor is fabricated for ultrasensitive microRNA-21 (miRNA-21)
detection, which includes an enzymatic biofuel cell (EBFC), DNA walkers, a digital …

The molecular biomarkers are molecules that are closely related to specific physiological
states. Numerous molecular biomarkers have been identified as targets for disease …

With the continuous development of biosensors, researchers have focused increasing
attention on various signal amplification strategies to pursue superior performance for more …

Circulating microRNAs (miRNAs) can be used as noninvasive biomarkers and are also
found circulating in body fluids such as blood. Dysregulated miRNA expression is …