Mesenchymal stem cells are culture-derived mesodermal progenitors isolatable from all
vascularized tissues. In spite of multiple fundamental, pre-clinical and clinical studies, the …

Bone defects stand out as one of the greatest challenges of reconstructive surgery. Fused
deposition modelling (FDM) allows for the printing of 3D scaffolds tailored to the morphology …

Thin endometrium has been widely recognized as a critical cause of infertility, recurrent
pregnancy loss, and placental abnormalities; however, access to effective treatment is a …

Although bone is an organ that displays potential for self-healing after damage, bone
regeneration does not occur properly in some cases, and it is still a challenge to treat large …

The vascular wall is comprised of distinct layers controlling angiogenesis, blood flow, vessel
anchorage within organs, and cell and molecule transit between blood and tissues …

Arterial calcification refers to the abnormal deposition of calcium salts in the arterial wall,
which results in vessel lumen stenosis and vascular remodeling. Studies increasingly show …

STUDY QUESTION What are the localization, characteristics and potential for tissue
regeneration of two perivascular stem cells, namely CD34+ adventitial cells and CD146+ …

Innate mesenchymal stem cells exhibiting multilineage differentiation and tissue (re)
generative—or pathogenic—properties reside in perivascular niches. Subsets of these …

Donor variation is a prominent critical issue limiting the applicability of cell-based therapies.
We hypothesized that batch effects during propagation of bone marrow stromal cells …

Osteoarthritis (OA) is the most common degenerative joint disease and a major cause of age-
related disability worldwide, mainly due to pain, the disease's main symptom. Although OA …