Clinical aspects of snakebite envenoming and its treatment in low-resource settings
DA Warrell, DJ Williams - The Lancet, 2023 - thelancet.com
There is increasing recognition of the public health importance of snakebite envenoming.
Worldwide annual incidence is likely to be 5 million bites, with mortality exceeding 150 000 …
Worldwide annual incidence is likely to be 5 million bites, with mortality exceeding 150 000 …
A current perspective on snake venom composition and constituent protein families
T Tasoulis, GK Isbister - Archives of Toxicology, 2023 - Springer
Snake venoms are heterogeneous mixtures of proteins and peptides used for prey
subjugation. With modern proteomics there has been a rapid expansion in our knowledge of …
subjugation. With modern proteomics there has been a rapid expansion in our knowledge of …
Comprehensive isoform-level analysis reveals the contribution of alternative isoforms to venom evolution and repertoire diversity
Animal venom systems have emerged as valuable models for investigating how novel
polygenic phenotypes may arise from gene evolution by varying molecular mechanisms …
polygenic phenotypes may arise from gene evolution by varying molecular mechanisms …
The genetic regulatory architecture and epigenomic basis for age-related changes in rattlesnake venom
MP Hogan, ML Holding, GS Nystrom… - Proceedings of the …, 2024 - National Acad Sciences
Developmental phenotypic changes can evolve under selection imposed by age-and size-
related ecological differences. Many of these changes occur through programmed …
related ecological differences. Many of these changes occur through programmed …
[HTML][HTML] Genome evolution and the future of phylogenomics of non-avian reptiles
DC Card, WB Jennings, SV Edwards - Animals, 2023 - mdpi.com
Simple Summary As a group of organisms, non-avian reptiles, most of which are the~
11,000 species of lizards and snakes, are an extraordinarily diverse group, displaying a …
11,000 species of lizards and snakes, are an extraordinarily diverse group, displaying a …
Origins, genomic structure and copy number variation of snake venom myotoxins
Crotamine, myotoxin a and homologs are short peptides that often comprise major fractions
of rattlesnake venoms and have been extensively studied for their bioactive properties …
of rattlesnake venoms and have been extensively studied for their bioactive properties …
[HTML][HTML] Gene communities in co-expression networks across different tissues
With the recent availability of tissue-specific gene expression data, eg, provided by the GTEx
Consortium, there is interest in comparing gene co-expression patterns across tissues. One …
Consortium, there is interest in comparing gene co-expression patterns across tissues. One …
ToxCodAn-Genome: an automated pipeline for toxin-gene annotation in genome assembly of venomous lineages
Background The rapid development of sequencing technologies resulted in a wide
expansion of genomics studies using venomous lineages. This facilitated research focusing …
expansion of genomics studies using venomous lineages. This facilitated research focusing …
Single-cell heterogeneity in snake venom expression is hardwired by co-option of regulators from progressively activated pathways
The ubiquitous cellular heterogeneity underlying many organism-level phenotypes raises
questions about what factors drive this heterogeneity and how these complex …
questions about what factors drive this heterogeneity and how these complex …
Morphological, functional, compositional and transcriptional constraints shape the distinct venom profiles of the assassin bug Sycanus croceovittatus
C Wu, L Li, Y Wang, S Wei, J Zhu - International Journal of Biological …, 2023 - Elsevier
Predatory bugs employ a salivary venom apparatus to generate complex venoms for
capturing and digesting prey. The venom apparatus consists of different glands for the …
capturing and digesting prey. The venom apparatus consists of different glands for the …