Neurotoxicity in acute and repeated organophosphate exposure

SX Naughton, AV Terry Jr - Toxicology, 2018 - Elsevier
The term organophosphate (OP) refers to a diverse group of chemicals that are found in
hundreds of products worldwide. As pesticides, their most common use, OPs are clearly …

Novel clinical toxicology and pharmacology of organophosphorus insecticide self-poisoning

M Eddleston - Annual review of pharmacology and toxicology, 2019 - annualreviews.org
Organophosphorus insecticide self-poisoning is a major global health problem, killing over
100,000 people annually. It is a complex multi-organ condition, involving the inhibition of …

Organophosphorus pesticides as modulating substances of inflammation through the cholinergic pathway

MR Camacho-Pérez, CE Covantes-Rosales… - International Journal of …, 2022 - mdpi.com
Organophosphorus pesticides (OPs) are widespread insecticides used for pest control in
agricultural activities and the control of the vectors of human and animal diseases. However …

The effects of N-acetylcysteine on inflammatory and oxidative stress biomarkers: A systematic review and meta-analysis of controlled clinical trials

AH Faghfouri, M Zarezadeh… - European journal of …, 2020 - Elsevier
Prolonged inflammation could be considered as the leading cause of chronic diseases such
as cardiovascular disorders, type two diabetes, and obesity. N-acetylcysteine (NAC) is …

N-Acetylcysteine Alleviated the Deltamethrin-Induced Oxidative Cascade and Apoptosis in Liver and Kidney Tissues

A Allam, A Abdeen, HP Devkota, SS Ibrahim… - International Journal of …, 2022 - mdpi.com
Deltamethrin (DLM) is a synthetic pyrethroid with anti-acaricide and insecticidal properties. It
is commonly used in agriculture and veterinary medicine. Humans and animals are exposed …

The therapeutic benefit of antioxidants on the outcome of acute aluminum phosphide poisoning: a systemic review and meta-analysis

ZK Sobh, A Abd-Elhameed - Toxicology Research, 2023 - academic.oup.com
This systematic review and meta-analysis pool evidence available from clinical trials to verify
the effect of antioxidants on the outcome of acute aluminum phosphide (AlP) poisoning. A …

N-acetyl-l-cysteine mediated regulation of DNA fragmentation, an apoptotic event, against methoxychlor toxicity in the granulosa cells of ovarian antral follicles

JK Bhardwaj, P Saraf - Mutation Research/Genetic Toxicology and …, 2020 - Elsevier
Abstract Methoxychlor (MXC), an organo-chlorine insecticide, is a reproductive toxicant in
females, causing apoptosis-mediated follicular atresia. To elucidate the potentials of …

[HTML][HTML] Organophosphate pesticides and new-onset diabetes mellitus: From molecular mechanisms to a possible therapeutic perspective

YL Chung, YC Hou, IK Wang, KC Lu… - World Journal of …, 2021 - ncbi.nlm.nih.gov
Organophosphate is a commonly used pesticide in the agricultural sector. The main action
of organophosphate focuses on acetylcholinesterase inhibition, and it therefore contributes …

Protective role of l-glutamic acid and l-cysteine in mitigation the chlorpyrifos-induced oxidative stress in rats

N Salyha, Y Salyha - Environmental toxicology and pharmacology, 2018 - Elsevier
Exposure to the organophosphorus insecticide chlorpyrifos (CPF) can lead to oxidative
stress. The aim of this work was to investigate and compare the protective effects of amino …

Protective effect of N-acetylcysteine on fenitrothion-induced toxicity: The antioxidant status and metabolizing enzymes expression in rats

AAA Galal, RA Ramadan, MMM Metwally… - Ecotoxicology and …, 2019 - Elsevier
The existence of fenitrothion (FNT) in the soil, water, and food products has harmful effects
on non-target organisms. Therefore, this study was conducted to evaluate the hepatotoxic …