Psychiatric face of COVID-19

L Steardo Jr, L Steardo, A Verkhratsky - Translational psychiatry, 2020 - nature.com
Abstract The Coronavirus Disease 2019 (COVID-19) represents a severe multiorgan
pathology which, besides cardio-respiratory manifestations, affects the function of the central …

The neuroimmunology of social-stress-induced sensitization

RG Biltz, CM Sawicki, JF Sheridan, JP Godbout - Nature immunology, 2022 - nature.com
Myriad clinical findings provide links between chronic stressors, inflammation, and mood
disorders. Furthermore, traumatic or chronic exposure to psychological stressors may …

Genes, environments, and time: the biology of adversity and resilience

WT Boyce, P Levitt, FD Martinez, BS McEwen… - …, 2021 - publications.aap.org
Exposures to adverse environments, both psychosocial and physicochemical, are prevalent
and consequential across a broad range of childhood populations. Such adversity …

Inflammation in fear-and anxiety-based disorders: PTSD, GAD, and beyond

V Michopoulos, A Powers, CF Gillespie… - …, 2017 - nature.com
The study of inflammation in fear-and anxiety-based disorders has gained interest as
growing literature indicates that pro-inflammatory markers can directly modulate affective …

The role of the immune system in posttraumatic stress disorder

S Katrinli, NCS Oliveira, JC Felger… - Translational …, 2022 - nature.com
Posttraumatic stress disorder (PTSD) develops in a subset of individuals upon exposure to
traumatic stress. In addition to well-defined psychological and behavioral symptoms, some …

From stress to inflammation and major depressive disorder: a social signal transduction theory of depression.

GM Slavich, MR Irwin - Psychological bulletin, 2014 - psycnet.apa.org
Major life stressors, especially those involving interpersonal stress and social rejection, are
among the strongest proximal risk factors for depression. In this review, we propose a …

Pathogenesis of depression: insights from human and rodent studies

C Ménard, GE Hodes, SJ Russo - Neuroscience, 2016 - Elsevier
Major depressive disorder (MDD) will affect one out of every five people in their lifetime and
is the leading cause of disability worldwide. Nevertheless, mechanisms associated with the …

Allele-specific FKBP5 DNA demethylation mediates gene–childhood trauma interactions

T Klengel, D Mehta, C Anacker, M Rex-Haffner… - Nature …, 2013 - nature.com
Although the fact that genetic predisposition and environmental exposures interact to shape
development and function of the human brain and, ultimately, the risk of psychiatric …

Cytokine targets in the brain: impact on neurotransmitters and neurocircuits

AH Miller, E Haroon, CL Raison… - Depression and …, 2013 - Wiley Online Library
Increasing attention has been paid to the role of inflammation in a host of illnesses including
neuropsychiatric disorders such as depression and anxiety. Activation of the inflammatory …

Stimulation of systemic low-grade inflammation by psychosocial stress

N Rohleder - Psychosomatic medicine, 2014 - journals.lww.com
Psychosocial stress is an important precursor of disease and reduced quality of life in
humans. The biological pathways between stress exposure and pathophysiological …