Practical considerations for quantitative light sheet fluorescence microscopy
Fluorescence microscopy has evolved from a purely observational tool to a platform for
quantitative, hypothesis-driven research. As such, the demand for faster and less phototoxic …
quantitative, hypothesis-driven research. As such, the demand for faster and less phototoxic …
Trace analysis of food by surface-enhanced Raman spectroscopy combined with molecular imprinting technology: Principle, application, challenges, and prospects
Surface-enhanced Raman spectroscopy (SERS) is a rapid detection method with high
sensitivity and simple pretreatment, but can be affected by interference from matrix …
sensitivity and simple pretreatment, but can be affected by interference from matrix …
Imagining the future of optical microscopy: everything, everywhere, all at once
H Balasubramanian, CM Hobson, TL Chew… - Communications …, 2023 - nature.com
The optical microscope has revolutionized biology since at least the 17th Century. Since
then, it has progressed from a largely observational tool to a powerful bioanalytical platform …
then, it has progressed from a largely observational tool to a powerful bioanalytical platform …
Dynamic label-free analysis of SARS-CoV-2 infection reveals virus-induced subcellular remodeling
N Saunders, B Monel, N Cayet, L Archetti… - Nature …, 2024 - nature.com
Assessing the impact of SARS-CoV-2 on organelle dynamics allows a better understanding
of the mechanisms of viral replication. We combine label-free holotomographic microscopy …
of the mechanisms of viral replication. We combine label-free holotomographic microscopy …
Believing is seeing–the deceptive influence of bias in quantitative microscopy
RM Lee, LR Eisenman, S Khuon… - Journal of Cell …, 2024 - journals.biologists.com
The visual allure of microscopy makes it an intuitively powerful research tool. Intuition,
however, can easily obscure or distort the reality of the information contained in an image …
however, can easily obscure or distort the reality of the information contained in an image …
Cochlear ribbon synapses in aged gerbils
In mammalian hearing, type-I afferent auditory nerve fibers comprise the basis of the afferent
auditory pathway. They are connected to inner hair cells of the cochlea via specialized …
auditory pathway. They are connected to inner hair cells of the cochlea via specialized …
High-fidelity optical diffraction tomography of live organisms using iodixanol refractive index matching
Optical diffraction tomography (ODT) enables the three-dimensional (3D) refractive index
(RI) reconstruction. However, when the RI difference between a sample and a medium …
(RI) reconstruction. However, when the RI difference between a sample and a medium …
Balance between the Cell Viability and Death in 3D
Cell death is a phenomenon, frequently perceived as an absolute event for cell, tissue and
the organ. However, the rising popularity and complexity of such 3D multicellular 'tissue …
the organ. However, the rising popularity and complexity of such 3D multicellular 'tissue …
Harnessing artificial intelligence to reduce phototoxicity in live imaging
E Gómez-de-Mariscal, M Del Rosario… - Journal of Cell …, 2024 - journals.biologists.com
Fluorescence microscopy is essential for studying living cells, tissues and organisms.
However, the fluorescent light that switches on fluorescent molecules also harms the …
However, the fluorescent light that switches on fluorescent molecules also harms the …
基于高通量液相色谱质谱技术的菌株筛选与关键分子定量分析研究进展
吴玉洁， 刘欣欣， 刘健慧， 杨开广， 随志刚， 张丽华… - 合成生物学, 2023 - synbioj.cip.com.cn
合成生物学是21 世纪新兴的交叉学科, 已经为医药, 化工, 能源, 食品和农业等领域带来了显著的
改变. 微生物细胞工厂(microbial cell factory, MCF) 的构建和应用是合成生物学的重要研究内容 …
改变. 微生物细胞工厂(microbial cell factory, MCF) 的构建和应用是合成生物学的重要研究内容 …