Growing evidence suggests that the gut microbiota modulates the efficacy and toxicity of
cancer therapy, most notably immunotherapy and its immune-related adverse effects. The …

Conceptual scientific and medical advances have led to a recent realization that there may
be no single, one-size-fits-all diet and that differential human responses to dietary inputs …

Ample evidence indicates that the gut microbiome is a tumor-extrinsic factor associated with
antitumor response to anti-programmed cell death protein-1 (PD-1) therapy, but …

Fatty liver associated with metabolic dysfunction is common, affects a quarter of the
population, and has no approved drug therapy. Although pharmacotherapies are in …

The Christensenellaceae, a recently described family in the phylum Firmicutes, is emerging
as an important player in human health. The relative abundance of Christensenellaceae in …

Gut microbiota and exercise have recently been shown to be interconnected. Both moderate
and intense exercise are typically part of the training regimen of endurance athletes, but they …

Coronary artery disease (CAD) is the most common health problem worldwide and remains
the leading cause of morbidity and mortality. Over the past decade, it has become clear that …

The gut microbiota is reported to be related to obesity, and visceral fat is reported to be
strongly associated with cardiovascular disease and overall mortality. However, the …

The importance of sampling from globally representative populations has been well
established in human genomics. In human microbiome research, however, we lack a full …

A growing number of human gut microbiome studies consistently describe differences
between human populations. Here, we review how factors related to host genetics, ethnicity …