tert‐Butyl Hydroperoxide (TBHP): Recent Progress in C−H Functionalization and Heteroatom‐Heteroatom Bond Formations
Abstract tert‐Butyl hydroperoxide (tBuOOH, TBHP) is a commonly used hydroperoxide in
many oxidation processes. The primary factors contributing to the increasing usefulness of …
many oxidation processes. The primary factors contributing to the increasing usefulness of …
Indoles as promising Therapeutics: A review of recent drug discovery efforts
NJ Pravin, RS Kavalapure, SG Alegaon, S Gharge… - Bioorganic …, 2024 - Elsevier
Indole, a fundamental heterocyclic core, has emerged as a cornerstone in the medicinal
chemistry due to its diverse biological activities and structural versatility. This aromatic …
chemistry due to its diverse biological activities and structural versatility. This aromatic …
l-Proline-catalysed synthesis of chromeno [2, 3-b] chromene from 4-hydroxy-2 H-chromene-2-thione and an anti-proliferative study
The reactivity of 4-hydroxy-2H-chromene-2-thione is investigated with aryl aldehydes and 5,
5-dimethylcylohexane-1, 3-dione (dimedone) in the presence of 20 mol% L-proline in …
5-dimethylcylohexane-1, 3-dione (dimedone) in the presence of 20 mol% L-proline in …
Pursuing Polypharmacology: Benzothiopyranoindoles as G-Quadruplex Stabilizers and Topoisomerase I Inhibitors for Effective Anticancer Strategies
S Salerno, E Barresi, M Roggia, B Natale… - ACS Medicinal …, 2024 - ACS Publications
Here, we explored the benzothiopyranoindole scaffold to develop antiproliferative agents
with a polypharmacological profile targeting both G-quadruplex (G4)-structures and …
with a polypharmacological profile targeting both G-quadruplex (G4)-structures and …
Reactivity study of 4-hydroxythiocoumarin: a novel synthetic route to fused chromono-thiophene and-thiopyran derivatives through solvent-dependent thio-Claisen …
UJ Goswami, A Xalxo, M Basumatary, K Soni… - New Journal of …, 2024 - pubs.rsc.org
The alkylation of 4-hydroxythiocoumarins (1a–f) was carried out with various allyl bromides
as well as propargyl bromides using K2CO3 (2 equiv.) in anhydrous acetone at room …
as well as propargyl bromides using K2CO3 (2 equiv.) in anhydrous acetone at room …
A Reactivity Study of 4-Hydroxy-2H-chromene-2-thione and 4-Hydroxy-2H-thiochromene-2-thione with tert-Butyl Nitrite and Aromatic Amines: An Environmentally …
The synthesis of biologically active coumarin-based hydrazone derivatives is achieved
through a one-pot, three-component reaction of 4-hydroxy-2H-chromene-2-thiones with …
through a one-pot, three-component reaction of 4-hydroxy-2H-chromene-2-thiones with …