Properties and functions of fibroblasts and myofibroblasts in myocardial infarction
The adult mammalian heart contains abundant interstitial and perivascular fibroblasts that
expand following injury and play a reparative role but also contribute to maladaptive fibrotic …
expand following injury and play a reparative role but also contribute to maladaptive fibrotic …
Fibroblasts in the infarcted, remodeling, and failing heart
C Humeres, NG Frangogiannis - JACC: Basic to Translational Science, 2019 - jacc.org
Expansion and activation of fibroblasts following cardiac injury is important for repair but
may also contribute to fibrosis, remodeling, and dysfunction. The authors discuss the …
may also contribute to fibrosis, remodeling, and dysfunction. The authors discuss the …
The roles and regulation of the actin cytoskeleton, intermediate filaments and microtubules in smooth muscle cell migration
DD Tang, BD Gerlach - Respiratory research, 2017 - Springer
Smooth muscle cell migration has been implicated in the development of respiratory and
cardiovascular systems; and airway/vascular remodeling. Cell migration is a polarized …
cardiovascular systems; and airway/vascular remodeling. Cell migration is a polarized …
Fibroblasts in myocardial infarction: a role in inflammation and repair
AV Shinde, NG Frangogiannis - Journal of molecular and cellular …, 2014 - Elsevier
Fibroblasts do not only serve as matrix-producing reparative cells, but exhibit a wide range
of functions in inflammatory and immune responses, angiogenesis and neoplasia. The adult …
of functions in inflammatory and immune responses, angiogenesis and neoplasia. The adult …
Cardiac fibroblast activation post-myocardial infarction: current knowledge gaps
Y Ma, RP Iyer, M Jung, MP Czubryt… - Trends in pharmacological …, 2017 - cell.com
In response to myocardial infarction (MI), the wound healing response of the left ventricle
(LV) comprises overlapping inflammatory, proliferative, and maturation phases, and the …
(LV) comprises overlapping inflammatory, proliferative, and maturation phases, and the …
The dynamic interplay between cardiac inflammation and fibrosis
TP Thomas, LA Grisanti - Frontiers in physiology, 2020 - frontiersin.org
Heart failure is a leading cause of death worldwide. While there are multiple etiologies
contributing to the development of heart failure, all cause result in impairments in cardiac …
contributing to the development of heart failure, all cause result in impairments in cardiac …
The role of calmodulin in tumor cell migration, invasiveness, and metastasis
A Villalobo, MW Berchtold - International Journal of Molecular Sciences, 2020 - mdpi.com
Calmodulin (CaM) is the principal Ca2+ sensor protein in all eukaryotic cells, that upon
binding to target proteins transduces signals encoded by global or subcellular-specific …
binding to target proteins transduces signals encoded by global or subcellular-specific …
The cardiac wound healing response to myocardial infarction
U Chalise, M Becirovic‐Agic… - WIREs mechanisms of …, 2023 - Wiley Online Library
Myocardial infarction (MI) is defined as evidence of myocardial necrosis consistent with
prolonged ischemia. In response to MI, the myocardium undergoes a series of wound …
prolonged ischemia. In response to MI, the myocardium undergoes a series of wound …
Potential clinical biomarkers and perspectives in diabetic cardiomyopathy
J Deng, F Yan, J Tian, A Qiao, D Yan - Diabetology & metabolic syndrome, 2023 - Springer
Diabetic cardiomyopathy (DCM) is a serious cardiovascular complication and the leading
cause of death in diabetic patients. Patients typically do not experience any symptoms and …
cause of death in diabetic patients. Patients typically do not experience any symptoms and …
[HTML][HTML] A high-salt diet promotes hypertrophic scarring through TRPC3-mediated mitochondrial Ca2+ homeostasis dysfunction
W Xia, Q Wang, S Lin, Y Wang, J Zhang, H Wang… - Heliyon, 2023 - cell.com
Diet High in salt content have been associated with cardiovascular disease and chronic
inflammation. We recently demonstrated that transient receptor potential canonical 3 …
inflammation. We recently demonstrated that transient receptor potential canonical 3 …