Substance use disorder (SUD) is a global public health concern that affects millions of
people worldwide. Considering current research, addiction has been noted as the last stage …

Excessive alcohol consumption is involved in 1/10 of deaths of US working-age adults and
costs the country around $250,000,000 yearly. While Alcohol Use Disorder (AUD) pathology …

Abstract Purpose of Review The following review will explore ketamine's antidepressant and
antisuicidal properties in adults, review of what is known about ketamine's safety in children …

Ketamine was first synthesized in the early 1960s in search for anesthetic compounds and
has been a mainstay for anesthesia since its approval by the United States Food and Drug …

Background Ketamine (KET) is administered to manage major depression in adolescent
patients. However, the long-term effects of juvenile KET exposure on memory-related tasks …

Early exposures to anesthetics can cause long-lasting changes in excitatory/inhibitory
synaptic transmission (E/I imbalance), an important mechanism for neurodevelopmental …

Background Few studies have previously evaluated the long-term impact of initiating the
combined use of alcohol and cocaine early-in-life during adolescence. Our preclinical study …

Elucidating the influence of social context on drug reward is critical for understanding
substance use disorders. Adolescents demonstrate enhanced sensitivity to drug and social …

Le Trouble de l'Usage d'Alcool (TUA) est une maladie psychiatrique caractérisée par une
consommation chronique et excessive d'alcool malgré des conséquences négatives sur la …

Few studies have previously evaluated the long-term impact of initiating the combined use of
alcohol and cocaine early-in-life during adolescence. Our preclinical study characterized …