Lignans are widely produced by various plant species; they are a class of natural products
that share structural similarity. They usually contain a core scaffold that is formed by two or …

Ischemia/reperfusion (I/R) injury is associated with substantial clinical implications, including
a wide range of organs such as the brain, kidneys, lungs, heart, and many others. I/R injury …

Curcumin, a phenolic compound extracted from Curcuma longa, is commonly used in Asia
as a spice and pigment and has several biological functions, particularly antioxidant …

Background Lignans are large group of polyphenols that are formed by the coupling of two
coniferyl alcohol residues. Based on their origin, lignans are broadly grouped into plant …

Nordihydroguaiaretic acid (NDGA) is a phenolic lignan obtained from Larrea tridentata, the
creosote bush found in Mexico and USA deserts, that has been used in traditional medicine …

The CREDENCE trial testing canagliflozin and the EMPA-REG OUTCOME trial testing
empagliflozin suggest different effects on acute kidney injury (AKI). AKI diagnosis was …

Inflammation is the primary response to infection and injury. Its beneficial effect is an
immediate resolution of the pathophysiological event. However, sustained production of …

Objectives To study the possible renoprotective effect of sildenafil against renal
ischemia/reperfusion (I/R) injury and its effect on the expression of some antioxidant …

For centuries, traditional medicine from plants (phytotherapy) was the only treatment for
infectious and non-infectious diseases. Although it is still practiced in several countries with …

In spite of the unequivocal efficacy of statins in reducing primary and secondary
cardiovascular events, the use of these drugs in a considerable number of patients is limited …