Sigma-2 Receptor/TMEM97 and PGRMC-1 Increase the Rate of Internalization of LDL by LDL Receptor through the Formation of a Ternary Complex

A Riad, C Zeng, CC Weng, H Winters, K Xu… - Scientific reports, 2018 - nature.com
CRISPR/Cas gene studies were conducted in HeLa cells where either PGRMC1, TMEM97
or both proteins were removed via gene editing. A series of radioligand binding studies …

The alpha-fetoprotein third domain receptor binding fragment: in search of scavenger and associated receptor targets

GJ Mizejewski - Journal of Drug Targeting, 2015 - Taylor & Francis
Recent studies have demonstrated that the carboxyterminal third domain of alpha-
fetoprotein (AFP-CD) binds with various ligands and receptors. Reports within the last …

Membrane cholesterol concentrations regulate the LDL-receptor's activity as revealed by fluorescence fluctuation analysis techniques

S Morales - 2022 - escholarship.mcgill.ca
The low-density lipoprotein receptor (LDLR) is the main metabolic cellular regulating
gateway of low-density lipoprotein (LDL) particles. LDLR-mediated internalization of LDL in …

Membrane Cholesterol Concentrations Regulate the LDL-Receptor's Activity as Revealed by Fluorescence Fluctuation Analysis Techniques

SM Vélez - 2022 - search.proquest.com
The low-density lipoprotein receptor (LDLR) is the main metabolic cellular regulating
gateway of low-density lipoprotein (LDL) particles. LDLR-mediated internalization of LDL in …