Molecular Mechanism of Quorum-Sensing in Enterococcus faecalis: Its Role in Virulence and Therapeutic Approaches

L Ali, MU Goraya, Y Arafat, M Ajmal, JL Chen… - International journal of …, 2017 - mdpi.com
Quorum-sensing systems control major virulence determinants in Enterococcus faecalis,
which causes nosocomial infections. The E. faecalis quorum-sensing systems include …

[HTML][HTML] Augmented dissemination of antibiotic resistance elicited by non-antibiotic factors

S Zhu, B Yang, Z Wang, Y Liu - Ecotoxicology and Environmental Safety, 2023 - Elsevier
The emergence and rapid spread of antibiotic resistance seriously compromise the clinical
efficacy of current antibiotic therapies, representing a serious public health threat worldwide …

Peptide pheromone signaling in Streptococcus and Enterococcus

LC Cook, MJ Federle - FEMS microbiology reviews, 2014 - academic.oup.com
Intercellular chemical signaling in bacteria, commonly referred to as quorum sensing (QS),
relies on the production and detection of compounds known as pheromones to elicit …

Secreting and sensing the same molecule allows cells to achieve versatile social behaviors

H Youk, WA Lim - Science, 2014 - science.org
Introduction Cells that simultaneously secrete and sense the same signaling molecule are
ubiquitous. Bacteria sense a quorum by secreting and sensing an autoinducer; T cells …

Insects, rodents, and pets as reservoirs, vectors, and sentinels of antimicrobial resistance

W Gwenzi, N Chaukura, N Muisa-Zikali, C Teta… - Antibiotics, 2021 - mdpi.com
This paper reviews the occurrence of antimicrobial resistance (AMR) in insects, rodents, and
pets. Insects (eg, houseflies, cockroaches), rodents (rats, mice), and pets (dogs, cats) act as …

Social behavior and decision making in bacterial conjugation

G Koraimann, MA Wagner - Frontiers in cellular and infection …, 2014 - frontiersin.org
Bacteria frequently acquire novel genes by horizontal gene transfer (HGT). HGT through the
process of bacterial conjugation is highly efficient and depends on the presence of …

Natural and artificial strategies to control the conjugative transmission of plasmids

M Getino, F de la Cruz - Microbiology spectrum, 2018 - Am Soc Microbiol
Conjugative plasmids are the main carriers of transmissible antibiotic resistance (AbR)
genes. For that reason, strategies to control plasmid transmission have been proposed as …

Possible drugs for the treatment of bacterial infections in the future: anti-virulence drugs

H Ogawara - The Journal of antibiotics, 2021 - nature.com
Antibiotic resistance is a global threat that should be urgently resolved. Finding a new
antibiotic is one way, whereas the repression of the dissemination of virulent pathogenic …

Regulation of gram-positive conjugation

V Kohler, W Keller, E Grohmann - Frontiers in microbiology, 2019 - frontiersin.org
Type IV Secretion Systems (T4SSs) are membrane-spanning multiprotein complexes
dedicated to protein secretion or conjugative DNA transport (conjugation systems) in …

The role of hosts, plasmids and environment in determining plasmid transfer rates: a meta-analysis

RJ Sheppard, AE Beddis, TG Barraclough - Plasmid, 2020 - Elsevier
Plasmids transfer at highly variable rates that spread over 10 orders of magnitude. While
rates have been measured for decades and it is known that the rates are affected bysome …