[HTML][HTML] Early detection of pancreatic cancer: opportunities and challenges

AD Singhi, EJ Koay, ST Chari, A Maitra - Gastroenterology, 2019 - Elsevier
Most patients with pancreatic ductal adenocarcinoma (PDAC) present with symptomatic,
surgically unresectable disease. Although the goal of early detection of PDAC is laudable …

[HTML][HTML] Sarcopenic obesity: hidden muscle wasting and its impact for survival and complications of cancer therapy

VE Baracos, L Arribas - Annals of Oncology, 2018 - Elsevier
Body composition, defined as the proportions and distribution of lean and fat tissues in the
human body, is an emergent theme in clinical oncology. Severe muscle depletion …

Nutritional support and therapy in pancreatic surgery: A position paper of the International Study Group on Pancreatic Surgery (ISGPS)

L Gianotti, MG Besselink, M Sandini, T Hackert… - Surgery, 2018 - Elsevier
Background The optimal nutritional therapy in the field of pancreatic surgery is still debated.
Methods An international panel of recognized pancreatic surgeons and pancreatologists …

[HTML][HTML] Sarcopenia and sarcopenic obesity are significantly associated with poorer overall survival in patients with pancreatic cancer: Systematic review and meta …

I Mintziras, M Miligkos, S Waechter… - International Journal of …, 2018 - Elsevier
Backround The role of sarcopenia and sarcopenic obesity in patients with pancreatic ductal
adenocarcinoma (PDAC) remains controversial. Material and Methods Medline and Web of …

Low skeletal muscle radiation attenuation and visceral adiposity are associated with overall survival and surgical site infections in patients with pancreatic cancer

DPJ van Dijk, MJAM Bakens… - Journal of cachexia …, 2017 - Wiley Online Library
Background Cancer cachexia and skeletal muscle wasting are related to poor survival. In
this study, quantitative body composition measurements using computed tomography (CT) …

Sarcopenia and myosteatosis are accompanied by distinct biological profiles in patients with pancreatic and periampullary adenocarcinomas

C Stretch, JM Aubin, B Mickiewicz, D Leugner… - PloS one, 2018 - journals.plos.org
Introduction Pancreatic and periampullary adenocarcinomas are associated with abnormal
body composition visible on CT scans, including low muscle mass (sarcopenia) and low …

The malnourished surgery patient: a silent epidemic in perioperative outcomes?

DGA Williams, J Molinger… - Current Opinion in …, 2019 - journals.lww.com
The recent publication of new surgical nutrition guidelines, the PONS score, and use of LBM
assessments will allow better identification and earlier intervention on perioperative …

Preoperative sarcopenia and post‐operative accelerated muscle loss negatively impact survival after resection of pancreatic cancer

MH Choi, SB Yoon, K Lee, M Song… - Journal of cachexia …, 2018 - Wiley Online Library
Background Sarcopenia and post‐operative accelerated muscle loss leading to cachexia
are commonly observed in patients with pancreatic cancer. This study aimed to assess the …

Association between changes in body composition and neoadjuvant treatment for pancreatic cancer

M Sandini, M Patiňo, CR Ferrone… - JAMA …, 2018 - jamanetwork.com
Importance Sarcopenia and sarcopenic obesity have been associated with poor outcomes
in unresectable pancreatic cancer (PC). Neoadjuvant treatment (NT) is used increasingly to …

Impact of different sarcopenia stages on the postoperative outcomes after radical gastrectomy for gastric cancer

DD Huang, CJ Zhou, SL Wang, ST Mao, XY Zhou… - Surgery, 2017 - Elsevier
Background The association between sarcopenia and postoperative outcomes has been
well reported. However, the impact of different sarcopenia stages on postoperative …