The superior colliculus is one of the most well-studied structures in the brain, and with each
new report, its proposed role in behavior seems to increase in complexity. Forty years of …

Behavior is readily classified into patterns of movements with inferred common goals—
actions. Goals may be discrete; movements are continuous. Through the careful study of …

The superior colliculus (SC) receives diverse and robust cortical inputs to drive a range of
cognitive and sensorimotor behaviors. However, it remains unclear how descending cortical …

The superior colliculus (SC) is the most prominent visual center in mice. Studies over the
past decade have greatly advanced our understanding of the function, organization, and …

Neuronal cell types are arranged in brain-wide circuits that guide behavior. In mice, the
superior colliculus innervates a set of targets that direct orienting and defensive actions. We …

Decision making is a cognitive process that mediates behaviors critical for survival.
Choosing spatial targets is an experimentally-tractable form of decision making that …

Alzheimer's disease (AD) is an increasingly common disease with massive personal and
economic costs. While it has long been known that AD impacts the visual system, there has …

Sensorimotor behaviors require processing of behaviorally relevant sensory cues and the
ability to select appropriate responses from a vast behavioral repertoire. Modulation by the …

Survival in a dynamic environment requires animals to plan future actions based on past
sensory evidence, known as motor planning. However, the neuronal circuits underlying this …

After been exposed to the visual input, in the first year of life, the brain experiences subtle
but massive changes apparently crucial for communicative/emotional and social human …