MicroRNAs (miRNAs) are defined as small non-coding RNAs~ 22 nt in length. They regulate
gene expression at a post-transcriptional level through complementary base pairing with the …

Metabolic disorders are characterized by the inability to properly use and/or store energy.
The burdens of metabolic disease, such as obesity or diabetes, are believed to arise through …

During the COVID-19 pandemic, Pfizer-BioNTech and Moderna successfully developed
nucleoside-modified mRNA lipid nanoparticle (LNP) vaccines. SARS-CoV-2 spike protein …

Post‐transcriptional regulation of messenger RNAs (mRNAs)(ie, mechanisms that control
translation, stability and localization) is a critical focal point in spatiotemporal regulation of …

Circular RNAs (circRNAs) are reported to act as important regulators in cancers. CircRNA
RAPGEF5 (cRAPGEF5) is derived from exons 2–6 of the RAPGEF5 gene and may promote …

As it is well known, messenger RNA has many regulatory regions along its sequence length.
One of them is the 5′ untranslated region (5'UTR), which itself contains many regulatory …

Scope Synonymous codon usage has been a focus of investigation since the discovery of
the genetic code and its redundancy. The occurrences of synonymous codons vary between …

The subset of regulatory T (Treg) cells, with its specific transcription Foxp3, is a unique cell
type for the maintenance of immune homeostasis by controlling effector T (Teff) cell …

Human prion protein and prion-like protein misfolding are widely recognized as playing a
causal role in many neurodegenerative diseases. Based on in vitro and in vivo experimental …

Accumulating evidences suggest that circular RNAs play vital roles in human cancers.
Previously, we found that circHIPK3 suppressed invasion of bladder cancer cells via …