Deconstructing the functional neuroanatomy of the choroid plexus: an ontogenetic perspective for studying neurodevelopmental and neuropsychiatric disorders

BKY Bitanihirwe, P Lizano, TUW Woo - Molecular Psychiatry, 2022 - nature.com
The choroid plexus (CP) is a delicate and highly vascularized structure in the brain
comprised of a dense network of fenestrated capillary loops that help in the synthesis …

Could CRP be a differential biomarker of illness stages in schizophrenia? A systematic review and meta-analysis

V Lestra, B Romeo, C Martelli, A Benyamina… - Schizophrenia …, 2022 - Elsevier
Background Patients with schizophrenia display peripheral inflammation but the impact of
illness phase is not clear. Our meta-analysis investigated the difference in CRP levels …

Brain microvascular endothelial cells and blood-brain barrier dysfunction in psychotic disorders

P Lizano, S Pong, S Santarriaga, D Bannai… - Molecular …, 2023 - nature.com
Although there is convergent evidence for blood-brain barrier (BBB) dysfunction and
peripheral inflammation in schizophrenia (SZ) and bipolar disorder (BD), it is unknown …

A preliminary choroid plexus volumetric study in individuals with psychosis

O Senay, M Seethaler, N Makris… - Human Brain …, 2023 - Wiley Online Library
The choroid plexus (ChP) is part of the blood‐cerebrospinal fluid barrier, regulating brain
homeostasis and the brain's response to peripheral events. Its upregulation and …

Choroid plexus enlargement exacerbates white matter hyperintensity growth through glymphatic impairment

Y Li, Y Zhou, W Zhong, X Zhu, Y Chen… - Annals of …, 2023 - Wiley Online Library
Objective Choroid plexus (CP) is a key regulator in cerebrospinal fluid production, but its
contribution to glymphatic clearance function and association with white matter …

[HTML][HTML] Choroid plexus enlargement is associated with neuroinflammation and reduction of blood brain barrier permeability in depression

N Althubaity, J Schubert, D Martins, T Yousaf… - NeuroImage: Clinical, 2022 - Elsevier
Background Recent studies have shown that choroid plexuses (CP) may be involved in the
neuro-immune axes, playing a role in the interaction between the central and peripheral …

[HTML][HTML] Sickness behaviour and depression: An updated model of peripheral-central immunity interactions

FE Turkheimer, M Veronese, V Mondelli, D Cash… - Brain, Behavior, and …, 2023 - Elsevier
Current research into mood disorders indicates that circulating immune mediators
participating in the pathophysiology of chronic somatic disorders have potent influences on …

[HTML][HTML] The association between allostatic load and brain: A systematic review

M Lenart-Bugla, D Szcześniak, B Bugla… - …, 2022 - Elsevier
Allostatic load (AL) refers to prolonged dysregulation related to chronic stress that affects
brain regions such as the hippocampus, amygdala, and prefrontal cortex (PFC). Higher …

Association of choroid plexus volume with serum biomarkers, clinical features, and disease severity in patients with frontotemporal lobar degeneration spectrum

M Assogna, E Premi, S Gazzina, A Benussi, NJ Ashton… - Neurology, 2023 - AAN Enterprises
Background and Objectives Choroid plexus (ChP) is emerging as a key brain structure in the
pathophysiology of neurodegenerative disorders. In this observational study, we …

Elevated salivary kynurenic acid levels related to enlarged choroid plexus and severity of clinical phenotypes in treatment-resistant schizophrenia

J Huang, J Tong, P Zhang, Y Zhou, Y Li, S Tan… - Brain, Behavior, and …, 2022 - Elsevier
Patients with treatment-resistant schizophrenia (TRS) suffer severe, long-term psychotic
symptoms and chronic stress. Salivary kynurenic acid (KYNA) and choroid plexus were …