Membrane-interacting antifungal peptides

C Struyfs, BPA Cammue, K Thevissen - Frontiers in cell and …, 2021 - frontiersin.org
The incidence of invasive fungal infections is increasing worldwide, resulting in more than
1.6 million deaths every year. Due to growing antifungal drug resistance and the limited …

Antifungal peptides as therapeutic agents

M Fernández de Ullivarri, S Arbulu… - Frontiers in Cellular …, 2020 - frontiersin.org
Fungi have been used since ancient times in food and beverage-making processes and,
more recently, have been harnessed for the production of antibiotics and in processes of …

Comparison of poison plate and agar well diffusion method determining the antifungal activity of protein fractions

C Erhonyota, GI Edo, FO Onoharigho - Acta Ecologica Sinica, 2023 - Elsevier
Medicinal plants are still being used as therapeutic agents in many developing nations
because they are more widely available. This research aimed to compare method/result …

Multitasking antimicrobial peptides in plant development and host defense against biotic/abiotic stress

RK Goyal, AK Mattoo - Plant Science, 2014 - Elsevier
Crop losses due to pathogens are a major threat to global food security. Plants employ a
multilayer defense against a pathogen including the use of physical barriers (cell wall) …

Recombinant expression, purification and antimicrobial activity of a novel antimicrobial peptide PaDef in Pichia pastoris

DM Meng, JF Zhao, X Ling, HX Dai, YJ Guo… - Protein Expression and …, 2017 - Elsevier
The antimicrobial peptide PaDef was isolated from Mexican avocado fruit and was reported
to inhibit the growth of Escherichia coli and Staphylococcus aureus in 2013. In this study, an …

Two-Step Isolation, Purification, and Characterization of Lectin from Zihua Snap Bean (Phaseolus vulgaris) Seeds

B Jiang, X Wang, L Wang, X Lv, D Li, C Liu, Z Feng - Polymers, 2019 - mdpi.com
A two-step method based on an aqueous two-phase system and Sephadex G-75 was used
to separate and purify lectin from the seeds of the Zihua snap bean. The preliminary …

Improved smallest peptides based on positive charge increase of the γ-core motif from D1 and their mechanism of action against Candida species

É de Oliveira Mello, GB Taveira… - International Journal …, 2019 - Taylor & Francis
Background Plant defensins have a hallmark γ-core motif (GXCX3-9C) that is related to their
antimicrobial properties. The aim of this work was to design synthetic peptides based on the …

Bioactive properties of greenhouse‐cultivated green beans (Phaseolus vulgaris L.) under biostimulants and water‐stress effect

SA Petropoulos, O Taofiq, Â Fernandes… - Journal of the …, 2019 - Wiley Online Library
BACKGROUND The scarcity of irrigation water is severely affecting global crop production.
In this context, biostimulants are increasingly used as alternatives means against abiotic …

Synthesis, Structure, and Activity of the Antifungal Plant Defensin PvD1

J Skalska, VM Andrade, GL Cena… - Journal of Medicinal …, 2020 - ACS Publications
Available treatments for invasive fungal infections have limitations, including toxicity and the
emergence of resistant strains. Therefore, there is an urgent need for alternative solutions …

Challenging metastatic breast cancer with the natural defensin Pv D 1

TN Figueira, FD Oliveira, I Almeida, ÉO Mello… - Nanoscale, 2017 - pubs.rsc.org
Metastatic breast cancer is a very serious life threatening condition that poses many
challenges for the pharmaceutical development of effective chemotherapeutics. As the …