The silent path to thousands of merozoites: the Plasmodium liver stage
Plasmodium sporozoites are deposited in the skin of their vertebrate hosts through the bite
of an infected female Anopheles mosquito. Most of these parasites find a blood vessel and …
of an infected female Anopheles mosquito. Most of these parasites find a blood vessel and …
Looking under the skin: the first steps in malarial infection and immunity
Malaria, which is caused by Plasmodium spp., starts with an asymptomatic phase, during
which sporozoites, the parasite form that is injected into the skin by a mosquito, develop into …
which sporozoites, the parasite form that is injected into the skin by a mosquito, develop into …
Role of host cell traversal by the malaria sporozoite during liver infection
J Tavares, P Formaglio, S Thiberge… - Journal of experimental …, 2013 - rupress.org
Malaria infection starts when the sporozoite stage of the Plasmodium parasite is injected into
the skin by a mosquito. Sporozoites are known to traverse host cells before finally invading a …
the skin by a mosquito. Sporozoites are known to traverse host cells before finally invading a …
Revisiting the mechanisms of immune evasion employed by human parasites
M Chulanetra, W Chaicumpa - Frontiers in cellular and infection …, 2021 - frontiersin.org
For the establishment of a successful infection, ie, long-term parasitism and a complete life
cycle, parasites use various diverse mechanisms and factors, which they may be inherently …
cycle, parasites use various diverse mechanisms and factors, which they may be inherently …
Genetically attenuated, P36p-deficient malarial sporozoites induce protective immunity and apoptosis of infected liver cells
MR Van Dijk, B Douradinha… - Proceedings of the …, 2005 - National Acad Sciences
Immunization with Plasmodium sporozoites that have been attenuated by γ-irradiation or
specific genetic modification can induce protective immunity against subsequent malaria …
specific genetic modification can induce protective immunity against subsequent malaria …
Identification of a transcription factor in the mosquito‐invasive stage of malaria parasites
M Yuda, S Iwanaga, S Shigenobu… - Molecular …, 2009 - Wiley Online Library
Gene expression in Plasmodium parasites undergoes significant changes in each
developmental stage, but the transcription factors (TFs) regulating these changes have not …
developmental stage, but the transcription factors (TFs) regulating these changes have not …
Proteomic Profiling of Plasmodium Sporozoite Maturation Identifies New Proteins Essential for Parasite Development and Infectivity
Plasmodium falciparum sporozoites that develop and mature inside an Anopheles mosquito
initiate a malaria infection in humans. Here we report the first proteomic comparison of …
initiate a malaria infection in humans. Here we report the first proteomic comparison of …
Host-cell invasion by malaria parasites: insights from Plasmodium and Toxoplasma
Recent years have seen tremendous progress in our understanding of malaria parasite
molecular biology. To a large extent, this progress follows significant developments in …
molecular biology. To a large extent, this progress follows significant developments in …
Spreading the seeds of million-murdering death*: metamorphoses of malaria in the mosquito
LA Baton, LC Ranford-Cartwright - Trends in parasitology, 2005 - cell.com
Plasmodium spp. undergo a complex obligate developmental cycle within their invertebrate
vectors that enables transmission between vertebrate hosts. This developmental cycle …
vectors that enables transmission between vertebrate hosts. This developmental cycle …
How pathogens use linear motifs to perturb host cell networks
Molecular mimicry is one of the powerful stratagems that pathogens employ to colonise their
hosts and take advantage of host cell functions to guarantee their replication and …
hosts and take advantage of host cell functions to guarantee their replication and …