Inflammation and aging: signaling pathways and intervention therapies
Aging is characterized by systemic chronic inflammation, which is accompanied by cellular
senescence, immunosenescence, organ dysfunction, and age-related diseases. Given the …
senescence, immunosenescence, organ dysfunction, and age-related diseases. Given the …
Design of therapeutic biomaterials to control inflammation
Z Tu, Y Zhong, H Hu, D Shao, R Haag… - Nature Reviews …, 2022 - nature.com
Inflammation plays an important role in the response to danger signals arising from damage
to our body and in restoring homeostasis. Dysregulated inflammatory responses occur in …
to our body and in restoring homeostasis. Dysregulated inflammatory responses occur in …
Rational design of immunomodulatory hydrogels for chronic wound healing
With all the advances in tissue engineering for construction of fully functional skin tissue,
complete regeneration of chronic wounds is still challenging. Since immune reaction to the …
complete regeneration of chronic wounds is still challenging. Since immune reaction to the …
Engineered biomaterials for in situ tissue regeneration
In situ tissue regeneration harnesses the body's regenerative potential to control cell
functions for tissue repair. The design of biomaterials for in situ tissue engineering requires …
functions for tissue repair. The design of biomaterials for in situ tissue engineering requires …
The role of the anti-inflammatory cytokine interleukin-10 in tissue fibrosis
Significance: Fibrosis is the endpoint of chronic disease in multiple organs, including the
skin, heart, lungs, intestine, liver, and kidneys. Pathologic accumulation of fibrotic tissue …
skin, heart, lungs, intestine, liver, and kidneys. Pathologic accumulation of fibrotic tissue …
[HTML][HTML] Hyaluronic acid and chondroitin sulfate (meth) acrylate-based hydrogels for tissue engineering: Synthesis, characteristics and pre-clinical evaluation
Hydrogels based on photocrosslinkable Hyaluronic Acid Methacrylate (HAMA) and
Chondroitin Sulfate Methacrylate (CSMA) are presently under investigation for tissue …
Chondroitin Sulfate Methacrylate (CSMA) are presently under investigation for tissue …
Role of interleukins in the pathogenesis of pulmonary fibrosis
YX She, QY Yu, XX Tang - Cell Death Discovery, 2021 - nature.com
Interleukins, a group of cytokines participating in inflammation and immune response, are
proved to be involved in the formation and development of pulmonary fibrosis. In this article …
proved to be involved in the formation and development of pulmonary fibrosis. In this article …
Toward a better regeneration through implant‐mediated immunomodulation: harnessing the immune responses
Tissue repair/regeneration, after implantation or injury, involves comprehensive
physiological processes wherein immune responses play a crucial role to enable tissue …
physiological processes wherein immune responses play a crucial role to enable tissue …
Recent progress on polysaccharide-based hydrogels for controlled delivery of therapeutic biomolecules
MI Rial-Hermida, A Rey-Rico… - ACS Biomaterials …, 2021 - ACS Publications
A plethora of applications using polysaccharides have been developed in recent years due
to their availability as well as their frequent nontoxicity and biodegradability. These polymers …
to their availability as well as their frequent nontoxicity and biodegradability. These polymers …
Novel drug delivery systems and disease models for pulmonary fibrosis
R Li, Y Jia, X Kong, Y Nie, Y Deng, Y Liu - Journal of Controlled Release, 2022 - Elsevier
Pulmonary fibrosis (PF) is a serious and progressive lung disease which is possibly life-
threatening. It causes lung scarring and affects lung functions including epithelial cell injury …
threatening. It causes lung scarring and affects lung functions including epithelial cell injury …