Next‐generation vaccines: nanoparticle‐mediated DNA and mRNA delivery

W Ho, M Gao, F Li, Z Li, XQ Zhang… - Advanced healthcare …, 2021 - Wiley Online Library
Nucleic acid vaccines are a method of immunization aiming to elicit immune responses akin
to live attenuated vaccines. In this method, DNA or messenger RNA (mRNA) sequences are …

Recent developments in the facile bio-synthesis of gold nanoparticles (AuNPs) and their biomedical applications

KX Lee, K Shameli, YP Yew, SY Teow… - International journal …, 2020 - Taylor & Francis
Gold nanoparticles (AuNPs) are extensively studied nanoparticles (NPs) and are known to
have profound applications in medicine. There are various methods to synthesize AuNPs …

Sustainable preparation of gold nanoparticles via green chemistry approach for biogenic applications

SI Asiya, K Pal, S Kralj, GS El-Sayyad… - Materials Today …, 2020 - Elsevier
Abstract Novel premises of 'Green Nanotechnology'have tremendous impacts towards
industrial scale revolution. The furtive extracted from natural precursors have driven to the …

Intracellularly generated immunological gold nanoparticles for combinatorial photothermal therapy and immunotherapy against tumor

D Zhang, T Wu, X Qin, Q Qiao, L Shang, Q Song… - Nano Letters, 2019 - ACS Publications
Gold nanoparticle (AuNP) has been widely used in cancer photothermal therapy (PTT) for
ablating accessible tumor, while it is insufficient for inhibiting tumor metastasis and relapse …

Carbene ligands in surface chemistry: from stabilization of discrete elemental allotropes to modification of nanoscale and bulk substrates

AV Zhukhovitskiy, MJ MacLeod, JA Johnson - Chemical Reviews, 2015 - ACS Publications
Carbenes are perhaps the most versatile reactive intermediates in chemistry. Since the
original visions of “methylene” by Dumas 1 in 1835 and a generalization of this vision by Nef …

Self‐assembly of antimicrobial peptides on gold nanodots: against multidrug‐resistant bacteria and wound‐healing application

WY Chen, HY Chang, JK Lu, YC Huang… - Advanced Functional …, 2015 - Wiley Online Library
Photoluminescent gold nanodots (Au NDs) are prepared via etching and codeposition of
hybridized ligands, an antimicrobial peptide (surfactin; SFT), and 1‐dodecanethiol (DT), on …

How toxic are gold nanoparticles? The state-of-the-art

I Fratoddi, I Venditti, C Cametti, MV Russo - Nano Research, 2015 - Springer
With the growing interest in the applications of gold nanoparticles in biotechnology and their
physiological effects, possible toxicity of gold nanoparticles is becoming an increasingly …

Understanding the seed-mediated growth of gold nanorods through a fractional factorial design of experiments

ND Burrows, S Harvey, FA Idesis, CJ Murphy - Langmuir, 2017 - ACS Publications
Since the development of simple, aqueous protocols for the synthesis of anisotropic metal
nanoparticles, research into many promising, valuable applications of gold nanorods has …

Progress in delivery of siRNA-based therapeutics employing nano-vehicles for treatment of prostate cancer

M Ashrafizadeh, K Hushmandi, E Rahmani Moghadam… - Bioengineering, 2020 - mdpi.com
Prostate cancer (PCa) accounts for a high number of deaths in males with no available
curative treatments. Patients with PCa are commonly diagnosed in advanced stages due to …

Advances in gold nanoparticle-based combined cancer therapy

K Bromma, DB Chithrani - Nanomaterials, 2020 - mdpi.com
According to the global cancer observatory (GLOBOCAN), there are approximately 18
million new cancer cases per year worldwide. Cancer therapies are largely limited to …