The pinacol rearrangement1 is a well-known reaction. It refers to the acid-catalyzed
transformation of 1, 2-diols to ketones or aldehydes by 1, 2-migration of a CÀC or CÀH bond …

Tandem Prins cyclization is a versatile method for the synthesis of fused/bridged/
spirotetrahydropyran scaffolds. Therefore, it has become a powerful tool for the …

Reagents and solvents were purified prior to use by the following procedures: InBr3 was
purchased from Sigma-Aldrich and used as obtained. CH2Cl2 (Reagent grade, Merck) was …

A domino synthesis of 2, 3-dialkylidenetetrahydrofurans based on Prins-type cyclization of 3,
5-diynols and aldehydes is described. In the present reaction, skeletal reorganization of the …

The fundamental spirane framework consists of two monocyclic rings linked in an orthogonal
relationship by a common ring atom. In spiranes with no annular heteroatom, four carbon …

The classical Prins cyclization has been one of the most intensively studied reactions during
the last two decades, and it has found many applications in key steps of natural product …

(R)-Citronellal undergoes initial ene reaction followed by Prins cyclization with aldehydes in
the presence of 5mol% of scandium triflate at ambient temperature to furnish octahydro-2H …

A cascade reaction of (E)-5-(arylamino) pent-3-en-1-ols and thiols with various aldehydes in
the presence of 30 mol% BF3· OEt2 in 1, 2-dichloroethane at 80° C affords a novel class of …

A novel Prins cascade process for the synthesis of 1, 9-dioxa-4-azaspiro [5.5] undecane
derivatives by the coupling of aldehydes with N-(4-hydroxy-2-methylenebutyl)-N-(2 …

A novel tandem cyclization strategy has been developed for the synthesis of hexahydro-1 H-
spiro [isoquinoline-4, 4′-pyran] derivatives through the condensation of 3-((benzylamino) …