Strategies for modelling endometrial diseases

AR Murphy, H Campo, JJ Kim - Nature Reviews Endocrinology, 2022 - nature.com
Each month during a woman's reproductive years, the endometrium undergoes vast
changes to prepare for a potential pregnancy. Diseases of the endometrium arise for …

Current updates on the role of microbiome in endometriosis: a narrative review

HL Ser, SJ Au Yong, MN Shafiee, NM Mokhtar, RAR Ali - Microorganisms, 2023 - mdpi.com
Endometriosis affects approximately 6 to 10% of reproductive-age women globally. Despite
much effort invested, the pathogenesis that promotes the development, as well as the …

Ferulic acid, ligustrazine, and tetrahydropalmatine display the anti-proliferative effect in endometriosis through regulating Notch pathway

X Dai, Q Wei, X Guo, Y Ding, X Yang, Y Zhang, X Xu… - Life Sciences, 2023 - Elsevier
Aims With an ambiguous anti-proliferative mechanism, the combination of ferulic acid,
ligustrazine, and tetrahydropalmatine (FLT) shows good anti-endometriosis (EMS) activity. In …

Reversible Mechanical Contraception and Endometriosis Treatment Using Stimuli‐Responsive Hydrogels

AHC Anthis, S Kilchenmann, M Murdeu… - Advanced …, 2024 - Wiley Online Library
Female sterilization via fallopian tube ligation is a common procedure; However, after the
operation, over 10% of women seek re‐fertilization, which is frequently unsuccessful. In …

Huayu Jiedu Fang protects ovarian function in mouse with endometriosis iron overload by inhibiting ferroptosis

J Ding, Q Zhao, Z Zhou, W Cheng… - Evidence‐Based …, 2022 - Wiley Online Library
Endometriosis (EM) is a common chronic inflammatory disease in women. Sampson's
retrograde menstruation theory is the most widely accepted theory of EM pathogenesis. The …

Fostering cardio-endometriosis: a call to action for a comprehensive understanding of cardiovascular disease in endometriosis

B Marchandot, E Faller, C Akladios… - European Journal of …, 2024 - academic.oup.com
Recently, a growing body of evidence has highlighted a concerning link between
endometriosis and cardiovascular disease. Endometriosis, a chronic, inflammatory …

Endometrium as control of endometriosis in experimental research: assessment of sample suitability

V Szegeczki, L Fazekas, M Kulcsár, D Reglodi, P Török… - Diagnostics, 2022 - mdpi.com
Endometriosis is a chronic gynecological disease that causes numerous severe symptoms
in affected women. Revealing alterations of the molecular processes in ectopic endometrial …

Vitamin D inhibited endometriosis development in mice model through interleukin-17 modulation

AR Burjiah, A Sa'adi, W Widjiati - Open Veterinary Journal, 2022 - ajol.info
Background: Endometriosis is a common, benign, estrogen-dependent, and chronic
gynecological disease. Immune system disturbance and inflammatory abnormalities were …

Endometriosis development in relation to hypoxia: a murine model study

M Hoffmann-Młodzianowska, RB Maksym, K Pucia… - Molecular …, 2024 - Springer
Background Endometriosis, due to its ambiguous symptoms, still remains one of the most
difficult female diseases to treat, with an average diagnosis time of 7–9 years. The changing …

Evaluation of the potential role of diethylstilbestrol on the induction of endometriosis in a rat model–An alternative approach

SP Krishnamoorthy, V Kalimuthu… - Biochemical and …, 2022 - Elsevier
Endometriosis is known to be a gynaecological condition characterised by persistent
inflammation and abnormal development of endometrial stroma and glands. Researchers …