Aspergillus fumigatus is a saprotrophic fungus; its primary habitat is the soil. In its ecological
niche, the fungus has learned how to adapt and proliferate in hostile environments. This …

Cell death is an essential immunological apparatus of host defense, but dysregulation of
mutually inclusive cell deaths poses severe threats during microbial and parasitic infections …

Aspergillus fumigatus is an important opportunistic fungal pathogen and causes invasive
pulmonary aspergillosis in conditions with compromised innate antifungal immunity …

Clinically relevant members of the Scedosporium/Pseudallescheria species complex and
Lomentospora prolificans are generally resistant against currently available systemic …

The genus Aspergillus is ubiquitous in the environment and contains a number of species,
primarily A. fumigatus, that cause mold-associated disease in humans. Humans inhale …

The immune response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is
a critical factor in the clinical presentation of COVID-19, which may range from asymptomatic …

The emergence of azole resistance in Aspergillus fumigatus as well as an increasing
frequency of multiresistant cryptic Aspergillus spp. necessitates exploration of new classes …

Abstract RIG-I–like receptors (RLR) are cytosolic RNA sensors that signal through the MAVS
adaptor to activate IFN responses against viruses. Whether the RLR family has broader …

Backgroud: Aspergillus fumigatus (A. fumigatus) is a clinically important fungal pathogen.
Invasive pulmonary aspergillosis (IPA) is the main fungal infection with increased morbidity …

Lungs balance threat from primary viral infection, secondary infection, and inflammatory
damage. Severe pulmonary inflammation induces vascular permeability, edema, and organ …