The endometrial immune environment of women with endometriosis

J Vallvé-Juanico, S Houshdaran… - Human reproduction …, 2019 - academic.oup.com
BACKGROUND Endometriosis, a common oestrogen-dependent inflammatory disorder in
women of reproductive age, is characterized by endometrial-like tissue outside its normal …

[HTML][HTML] The immunopathophysiology of endometriosis

LK Symons, JE Miller, VR Kay, RM Marks… - Trends in molecular …, 2018 - cell.com
Endometriosis is a chronic, inflammatory, estrogen-dependent disease characterized by the
growth of endometrial tissue outside of the uterine cavity. Although the etiology of …

[HTML][HTML] Pathogenesis of endometriosis: the genetic/epigenetic theory

PR Koninckx, A Ussia, L Adamyan, A Wattiez… - Fertility and sterility, 2019 - Elsevier
Objective To study the pathophysiology of endometriosis. Design Overview of observations
on endometriosis. Setting Not applicable. Patient (s) None. Interventions (s) None. Main …

[HTML][HTML] The role of the immune system in the development of endometriosis

M Abramiuk, E Grywalska, P Małkowska, O Sierawska… - Cells, 2022 - mdpi.com
Endometriosis is a chronic disease that affects about 10% of women of reproductive age. It
can contribute to pelvic pain, infertility or other conditions such as asthma, cardiovascular …

Endometriosis‐associated infertility: aspects of pathophysiological mechanisms and treatment options

T Tanbo, P Fedorcsak - Acta obstetricia et gynecologica …, 2017 - Wiley Online Library
Endometriosis is a common condition in women of reproductive age. In addition to pain,
endometriosis may also reduce fertility. The causes of infertility in women with endometriosis …

Pharmaceuticals targeting signaling pathways of endometriosis as potential new medical treatment: A review

SW Hung, R Zhang, Z Tan, JPW Chung… - Medicinal research …, 2021 - Wiley Online Library
Endometriosis (EM) is defined as endometrial tissues found outside the uterus. Growth and
development of endometriotic cells in ectopic sites can be promoted via multiple pathways …

[HTML][HTML] Peritoneal immune microenvironment of endometriosis: Role and therapeutic perspectives

S Chen, Y Liu, Z Zhong, C Wei, Y Liu… - Frontiers in Immunology, 2023 - frontiersin.org
Endometriosis, an estrogen-dependent chronic inflammatory disease characterized by the
growth of endometrium-like tissues outside the uterine cavity, affects 10% of reproductive …

[HTML][HTML] Pathogenesis of deep endometriosis

S Gordts, P Koninckx, I Brosens - Fertility and sterility, 2017 - Elsevier
The pathophysiology of (deep) endometriosis is still unclear. As originally suggested by
Cullen, change the definition “deeper than 5 mm” to “adenomyosis externa.” With the …

[PDF][PDF] Estrogen receptor β modulates apoptosis complexes and the inflammasome to drive the pathogenesis of endometriosis

SJ Han, SY Jung, SP Wu, SM Hawkins, MJ Park, S Kyo… - Cell, 2015 - cell.com
Alterations in estrogen-mediated cellular signaling play an essential role in the
pathogenesis of endometriosis. In addition to higher estrogen receptor (ER) β levels …

Immunology of endometriosis

LGC Riccio, P Santulli, L Marcellin, MS Abrão… - Best practice & research …, 2018 - Elsevier
The pathophysiology of endometriosis is not completely understood, but an aberrant
immune response in the peritoneal environment seems to be crucial for the proliferation of …