Monoamine oxidase inhibition by plant-derived β-carbolines; implications for the psychopharmacology of tobacco and ayahuasca

I Berlowitz, K Egger, P Cumming - Frontiers in pharmacology, 2022 - frontiersin.org
The monoamine oxidases (MAOs) are flavin-containing amine oxidoreductases responsible
for metabolism of many biogenic amine molecules in the brain and peripheral tissues …

[HTML][HTML] Current progress in neuroimaging research for the treatment of major depression with electroconvulsive therapy

XK Li, HT Qiu - World Journal of Psychiatry, 2022 - ncbi.nlm.nih.gov
Electroconvulsive therapy (ECT) uses a certain amount of electric current to pass through
the head of the patient, causing convulsions throughout the body, to relieve the symptoms of …

Comparison of Monoamine Oxidase-A, Aβ Plaques, Tau, and Translocator Protein Levels in Postmortem Human Alzheimer's Disease Brain

AU Syed, C Liang, KK Patel, R Mondal… - International journal of …, 2023 - mdpi.com
Increased monoamine oxidase-A (MAO-A) activity in Alzheimer's disease (AD) may be
detrimental to the point of neurodegeneration. To assess MAO-A activity in AD, we …

Lower amygdala fatty acid amide hydrolase in violent offenders with antisocial personality disorder: an [11C]CURB positron emission tomography study

NJ Kolla, I Boileau, K Karas, JJ Watts, P Rusjan… - Translational …, 2021 - nature.com
Antisocial personality disorder (ASPD) imposes a high societal burden given the repetitive
reactive aggression that affected individuals perpetrate. Since the brain endocannabinoid …

Impact of genetic variants within serotonin turnover enzymes on human cerebral monoamine oxidase A in vivo

M Spies, M Murgaš, C Vraka, C Philippe… - Translational …, 2023 - nature.com
Variants within the monoamine oxidase A (MAO-A, MAOA) and tryptophan hydroxylase 2
(TPH2) genes, the main enzymes in cerebral serotonin (5-HT) turnover, affect risk for …

Effects of electroconvulsive therapy on cerebral A1 adenosine receptor availability: a PET study in patients suffering from treatment-resistant major depressive …

T Kroll, M Grözinger, A Matusch, D Elmenhorst… - Frontiers in …, 2023 - frontiersin.org
Introduction Sleep deprivation and electroconvulsive therapy (ECT) effectively ameliorate
symptoms in major depressive disorder (MDD). In rodents, both are associated with an …

Neurobiological mechanisms of electroconvulsive therapy for depression: Insights into hippocampal volumetric increases from clinical and preclinical studies

Y Abe, VJ Erchinger, OT Ousdal… - Journal of …, 2024 - Wiley Online Library
Depression is a highly prevalent and disabling psychiatric disorder. The hippocampus,
which plays a central role in mood regulation and memory, has received considerable …

Sargassum horneri Extract Attenuates Depressive-like Behaviors in Mice Treated with Stress Hormone

I Park, J Kim, M Kim, DW Lim, J Jung, MJ Kim, J Song… - Antioxidants, 2023 - mdpi.com
Sargassum horneri, a brown seaweed, is known for its various health benefits; however,
there are no reports on its effects on depression. This study aimed to investigate the …

[HTML][HTML] High-dose testosterone treatment reduces monoamine oxidase A levels in the human brain: A preliminary report

GS Kranz, M Spies, C Vraka, U Kaufmann… - …, 2021 - Elsevier
The sex hormones testosterone and estradiol influence brain structure and function and are
implicated in the pathogenesis, prevalence and disease course of major depression. Recent …

[HTML][HTML] Correlation of receptor density and mRNA expression patterns in the human cerebral cortex

M Murgaš, P Michenthaler, MB Reed, G Gryglewski… - Neuroimage, 2022 - Elsevier
Abstract Changes in distribution of associated molecular targets have been reported across
several neuropsychiatric disorders. However, the high-resolution topology of most proteins …