Currently, there is a growing demand by our society, authorities and science to increase the
knowledge about the quality of food and its relationship with health and disease. Untargeted …

Adipose tissue has been the subject of research for a very long time. Many studies perform a
comprehensive analysis of different types of adipose tissue with an emphasis on brown …

Dexamethasone (Dex) is a synthetic glucocorticoid (GC) drug commonly used clinically for
the treatment of several inflammatory and immune-mediated diseases. Despite its broad …

Tissue metabolomics can play an important role in biological studies and biomarker
discovery. However, high-coverage metabolome analysis of tissue samples remains a …

Mango consumption has shown bioactive properties against several diseases like diabetes,
therefore, we evaluated how a mango-supplemented diet affects metabolic pathways in …

The ketogenic diet is highly effective at attenuating seizures in refractory epilepsy, and
accumulating evidence in the literature suggests that it may be beneficial in autism. To our …

Senile plaque formation as a consequence of amyloid-β peptide (Aβ) aggregation
constitutes one of the main hallmarks of Alzheimer's disease (AD). This pathology is …

Background/objectives There is a growing appreciation for individual responses to diet. In a
previous study, mouse strain-specific responses to American and ketogenic diets were …

Nutritional changes during developmental windows are of particular concern in offspring
metabolic disease. Questions are emerging concerning the role of maternal weight changes …

Objective Obesity is a leading risk factor for both the incidence and progression of
osteoarthritis (OA). Omic technologies, including transcriptomics and metabolomics are …