Mast cells, neuroinflammation and pain in fibromyalgia syndrome

TC Theoharides, I Tsilioni, M Bawazeer - Frontiers in Cellular …, 2019 - frontiersin.org
Fibromyalgia Syndrome (FMS) is a disorder of chronic, generalized muscular pain,
accompanied by sleep disturbances, fatigue and cognitive dysfunction. There is no definitive …

Estrogen receptors in pain modulation: cellular signaling

Q Chen, W Zhang, N Sadana, X Chen - Biology of sex Differences, 2021 - Springer
Sensory perception and emotional disorders are disproportionally represented in men and
women and are thus thought to be modulated by different sex hormones in various …

[HTML][HTML] Estrogen alleviates neuropathic pain induced after spinal cord injury by inhibiting microglia and astrocyte activation

JY Lee, HY Choi, BG Ju, TY Yune - … Acta (BBA)-Molecular Basis of Disease, 2018 - Elsevier
Neuropathic pain after spinal cord injury (SCI) is developed in about 80% of SCI patients
and there is no efficient therapeutic drug to alleviate SCI-induced neuropathic pain. Here we …

Thalamic activity and biochemical changes in individuals with neuropathic pain after spinal cord injury

SM Gustin, PJ Wrigley, AM Youssef, L McIndoe… - PAIN®, 2014 - Elsevier
There is increasing evidence relating thalamic changes to the generation and/or
maintenance of neuropathic pain. We have recently reported that neuropathic orofacial pain …

[HTML][HTML] The neuroprotective effects of estrogen and estrogenic compounds in spinal cord injury

A Shvetcov, MJ Ruitenberg, F Delerue, WA Gold… - Neuroscience & …, 2023 - Elsevier
Spinal cord injury (SCI) occurs when the spinal cord is damaged from either a traumatic
event or disease. SCI is characterised by multiple injury phases that affect the transmission …

[HTML][HTML] Daily fluctuations of progesterone and testosterone are associated with fibromyalgia pain severity

M Schertzinger, K Wesson-Sides, L Parkitny… - The Journal of …, 2018 - Elsevier
The purpose of this longitudinal blood sampling study was to examine relationships
between sex hormones and fibromyalgia pain. Eight women meeting case definition criteria …

Sex differences in pain along the neuraxis

P Presto, M Mazzitelli, R Junell, Z Griffin… - …, 2022 - Elsevier
Despite the overwhelming female-predominance in chronic pain disorders, preclinical pain
studies have historically excluded females as research subjects. Male-biased explanations …

Hydrogen-rich water attenuates brain damage and inflammation after traumatic brain injury in rats

R Tian, Z Hou, S Hao, W Wu, X Mao, X Tao, T Lu, B Liu - Brain Research, 2016 - Elsevier
Inflammation and oxidative stress are the two major causes of apoptosis after traumatic brain
injury (TBI). Most previous studies of the neuroprotective effects of hydrogen-rich water on …

[HTML][HTML] On the therapeutic targets and pharmacological treatments for pain relief following spinal cord injury: A mechanistic review

S Fakhri, F Abbaszadeh, M Jorjani - Biomedicine & Pharmacotherapy, 2021 - Elsevier
Spinal cord injury (SCI) is globally considered as one of the most debilitating disorders,
which interferes with daily activities and life of the affected patients. Despite many …

[HTML][HTML] HSP70 alleviates spinal cord injury by activating the NF-kB pathway

B Xu, J Wang, S Liu, H Liu, X Zhang, J Shi… - … of Musculoskeletal & …, 2021 - ncbi.nlm.nih.gov
Objectives: Spinal cord injury (SCI) is an acute traumatic lesion of neurons in the spinal cord
which has a high prevalence in the world, and has no effective surgical treatment. HSP70 is …