Regulation of glutaminase activity and glutamine metabolism

NP Curthoys, M Watford - Annual review of nutrition, 1995 - annualreviews.org
Glutamine is synthesized primarily in skeletal muscle, lungs, and adipose tissue. Plasma
glutamine plays an important role as a carrier of nitrogen, carbon, and energy between …

Mitochondrial metabolism of glutamine and glutamate and its physiological significance.

Z Kovacevic, JD McGivan - Physiological reviews, 1983 - journals.physiology.org
The amino acids glutamine and glutamic acid (glutamate) are of central importance in the
metabolic and biosynthetic pathways of all living organisms-animals, plants, and bacteria. In …

Grade-dependent metabolic reprogramming in kidney cancer revealed by combined proteomics and metabolomics analysis

HI Wettersten, AA Hakimi, D Morin, C Bianchi… - Cancer research, 2015 - AACR
Kidney cancer [or renal cell carcinoma (RCC)] is known as “the internist's tumor” because it
has protean systemic manifestations, suggesting that it utilizes complex, nonphysiologic …

[图书][B] The kidney

BM Brenner, FC Rector - 1976 - books.google.com
Page 1 0349-4 Supreme Court Appellate term SSOCIATION OF THE BAR с CITY OF NE
YORK 1928 Vol 25 October Term Page 2 DEC 28 1928 155454 Page 3 766 New York …

Acidosis induces reprogramming of cellular metabolism to mitigate oxidative stress

G LaMonte, X Tang, JLY Chen, J Wu, CKC Ding… - Cancer & …, 2013 - Springer
Background A variety of oncogenic and environmental factors alter tumor metabolism to
serve the distinct cellular biosynthetic and bioenergetic needs present during oncogenesis …

[HTML][HTML] Renal ammonia metabolism and transport

ID Weiner, JW Verlander - Comprehensive Physiology, 2013 - ncbi.nlm.nih.gov
Renal ammonia metabolism and transport mediates a central role in acid-base homeostasis.
In contrast to most renal solutes, the majority of renal ammonia excretion derives from …

Ammonia transporters and their role in acid-base balance

ID Weiner, JW Verlander - Physiological reviews, 2017 - journals.physiology.org
Acid-base homeostasis is critical to maintenance of normal health. Renal ammonia
excretion is the quantitatively predominant component of renal net acid excretion, both …

Ammonia metabolism

RL Tannen - American Journal of Physiology-Renal …, 1978 - journals.physiology.org
The pathways responsible for an the mechanisms underlying the adaptive increase in
ammonia production in response to acidosis are considered. It seems unlikely that the …

Oyster (Crassostrea gigas) ferritin relieves lead-induced liver oxidative damage via regulating the mitophagy

H Li, X Xia, S Cheng, J Zang, Z Wang, M Du - International Journal of …, 2023 - Elsevier
Lead can induce oxidative stress and increase lipid peroxidation in biofilms, leading to liver
damage and physiological dysfunction. This study aimed to investigate how oyster ferritin …

Sites of enzyme activity along the nephron

U Schmidt, WG Guder - Kidney international, 1976 - Elsevier
Renal tubular functions can be characterized as energy-consuming transport processes
which are driven by metabolic energy-yielding reactions. In this context it has been argued …