[HTML][HTML] Advances and challenges in the treatment of lung cancer

Y Li, B Yan, S He - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Lung cancer accounts for a relatively high proportion of malignant tumors. As the most
prevalent type of lung cancer, non-small cell lung cancer (NSCLC) is characterized by high …

Nanotechnology-empowered lung cancer therapy: from EMT role in cancer metastasis to application of nanoengineered structures for modulating growth and …

HM Saleem, P Ramaiah, J Gupta, AT Jalil… - Environmental …, 2023 - Elsevier
Lung cancer is one of the leading causes of death in both males and females, and it is the
first causes of cancer-related deaths. Chemotherapy, surgery and radiotherapy are …

Combined miR-181a-5p and ag nanoparticles are effective against oral Cancer in a mouse model

G Xu, X Song, X Wang, R Xue, X Yan… - International Journal …, 2024 - Taylor & Francis
Purpose Oral squamous cell carcinoma is the most common type of malignant tumor in the
head and neck region. Despite advancements, metastasis and recurrence rates remain …

PDZ and LIM domain-encoding genes: their role in cancer development

X Jiang, Z Xu, S Jiang, H Wang, M Xiao, Y Shi, K Wang - Cancers, 2023 - mdpi.com
Simple Summary There are three subfamilies of human PDZ-LIM family proteins with a total
of 10 protein molecules, and PDZ-LIM family proteins serve as a class of scaffolding proteins …

Bioengineered Nanomaterials for siRNA Therapy of Chemoresistant Cancers

M Sanati, CG Figueroa-Espada, EL Han, MJ Mitchell… - ACS …, 2024 - ACS Publications
Chemoresistance remains a long-standing challenge after cancer treatment. Over the last
two decades, RNA interference (RNAi) has emerged as a gene therapy modality to sensitize …

Recent advances in mesoporous silica nanoparticles delivering siRNA for cancer treatment

X Xie, T Yue, W Gu, WY Cheng, L He, WY Ren, F Li… - Pharmaceutics, 2023 - mdpi.com
Silencing genes using small interfering (si) RNA is a promising strategy for treating cancer.
However, the curative effect of siRNA is severely constrained by low serum stability and cell …

New insights into nanosystems for non-small-cell lung cancer: diagnosis and treatment

P Jiang, B Liang, Z Zhang, B Fan, L Zeng, Z Zhou… - RSC …, 2023 - pubs.rsc.org
Lung cancer is caused by a malignant tumor that shows the fastest growth in both incidence
and mortality and is also the greatest threat to human health and life. At present, both in …

Cutting-edge advancements in anticancer drug delivery and scope for theranostics using biocompatible multifunctional mesoporous silica nanoparticles

S Sarnaik, D Bhatane, SR Pamshong… - Journal of Drug Delivery …, 2024 - Elsevier
With the advancement in nanotechnology, treatment of cancer has improved significantly in
the past few decades. However, the hunt for exciting new generation of nanocarriers has no …

Nanotechnology boosts the efficiency of tumor diagnosis and therapy

Y Yang, M Lin, M Sun, GQ Zhang, J Guo… - … in Bioengineering and …, 2023 - frontiersin.org
The incidence and mortality of cancer are gradually increasing. The highly invasive and
metastasis of tumor cells increase the difficulty of diagnosis and treatment, so people pay …