Simple Summary Cellular senescence consists of a permanent block of cell proliferation in
the presence of an active metabolism. It is a physiological process occurring when cells …

Targeted cancer therapies have revolutionized the treatment of the disease in the past
decade. The tyrosine kinase inhibitor (TKI) class of drugs is a widely used option for treating …

Senescence is a special state of tumor suppression induced by cell cycle arrest. However,
releasing senescence-associated secretory phenotypes by senescent cells could provide …

In recent years, the Japanese population has been aging and the risk of contracting various
age-related diseases has increased. Thus, there is a need to analyze components that are …

Axitinib is an orally available inhibitor of tyrosine kinases, with high specificity for vascular
endothelial growth factor receptors (VEGFRs) 1, 2, and 3. It is approved for the treatment of …

目的: 探讨L-茶氨酸对D-半乳糖诱导人脐静脉内皮细胞(HUVECs) 和心肌细胞(H9c2)
损伤的保护作用. 方法: 通过D-半乳糖诱导HUVECs 和H9c2 细胞损伤. 采用CCK8 …

Cellular senescence participates to fundamental processes like tissue remodeling in embryo
development, wound healing and inhibition of preneoplastic cell growth. Most senescent …

Objective: To investigate the protective effects of L-theanine against D-galactose-induced
injury of human umbilical vein endothelial cells (HUVECs) and cardiomyocytes (H9c2) …