Membrane proteins perform a host of vital cellular functions. Deciphering the molecular
mechanisms whereby they fulfill these functions requires detailed biophysical and structural …

Order parameters from deuterium NMR are often used to validate or calibrate molecular
dynamics simulations. This paper gives a short overview of the literature in which …

It is shown that molecular structure and dynamics of a uniformly labeled membrane protein
can be studied under magic-angle-spinning conditions. For this purpose, dipolar recoupling …

α-Helical membrane proteins fulfill many vital roles in all living cells and constitute the
majority of drug targets. However, their relevance is in no way paralleled by our current …

Phospholamban (PLN) regulates calcium translocation within cardiac myocytes by shifting
sarco (endo) plasmic reticulum Ca2+-ATPase (SERCA) affinity for calcium. Although the …

We have used neutron spin echo (NSE) spectroscopy to study the effect of bilayer thickness
and monounsaturation (existence of a single double bond on one of the aliphatic chains) on …

Polyphenols are bioactive natural products that appear to act against a wide range of
pathologies. Mechanisms of activity have not been established, but recent studies have …

Membrane proteins and polycyclic lipids like cholesterol and hopanoids coordinate
phospholipid bilayer ordering. This phenomenon manifests as partitioning of the liquid …

Block copolymers composed of poly (ethylene oxide)(PEO) and poly (propylene
oxide)(PPO) have been widely used in cell membrane stabilization and permeabilization. To …

Poloxamers consisting of poly (ethylene oxide)(PEO) and poly (propylene oxide) segments
can protect cell membranes against various forms of stress. We investigated the role of the …