Microtubule-associated proteins (MAPs) were initially discovered as proteins that bind to
and stabilize microtubules. Today, an ever-growing number of MAPs reveals a more …

Classical microtubule‐associated proteins (MAPs) were originally identified based on their
co‐purification with microtubules assembled from mammalian brain lysate. They have since …

Within cells, motor and non-motor microtubule-associated proteins (MAPs) simultaneously
converge on the microtubule. How the binding activities of non-motor MAPs are coordinated …

Many eukaryotic cells distribute their intracellular components asymmetrically through
regulated active transport driven by molecular motors along microtubule tracks. While …

Kinesin-1 is responsible for microtubule-based transport of numerous cellular cargoes.
Here, we explored the regulation of kinesin-1 by MAP7 proteins. We found that all four …

Tau is a multifunctional microtubule-associated protein in the neuron. For decades, tau's
main function in neurons has been broadly accepted as stabilizing microtubules in the axon; …

Regulation of directed axon guidance and branching during development is essential for the
generation of neuronal networks. However, the molecular mechanisms that underlie …

Neuronal cell morphogenesis depends on proper regulation of microtubule-based transport,
but the underlying mechanisms are not well understood. Here, we report our study of MAP7 …

Axons are the slender, cable-like, up to meter-long projections of neurons that electrically
wire our brains and bodies. In spite of their challenging morphology, they usually need to be …

Microtubules (MTs) are key components of the eukaryotic cytoskeleton and are essential for
intracellular organization, organelle trafficking and mitosis. MT tasks depend on binding and …