Local cellular interactions during the self-organization of stem cells
C Schröter, KS Stapornwongkul, V Trivedi - Current Opinion in Cell Biology, 2023 - Elsevier
Stem cell models for early mammalian development offer new experimental opportunities to
access spatio-temporal details of the cell-cell interactions that govern cell differentiation and …
access spatio-temporal details of the cell-cell interactions that govern cell differentiation and …
Haematopoietic development and HSC formation in vitro: promise and limitations of gastruloid models
L Dijkhuis, A Johns, D Ragusa… - Emerging Topics in …, 2023 - portlandpress.com
Haematopoietic stem cells (HSCs) are the most extensively studied adult stem cells. Yet, six
decades after their first description, reproducible and translatable generation of HSC in vitro …
decades after their first description, reproducible and translatable generation of HSC in vitro …
Information content and optimization of self-organized developmental systems
DB Brückner, G Tkačik - Proceedings of the National …, 2024 - National Acad Sciences
A key feature of many developmental systems is their ability to self-organize spatial patterns
of functionally distinct cell fates. To ensure proper biological function, such patterns must be …
of functionally distinct cell fates. To ensure proper biological function, such patterns must be …
Robust axis elongation by Nodal-dependent restriction of BMP signaling
A Schauer, K Pranjic-Ferscha, R Hauschild… - …, 2024 - journals.biologists.com
Embryogenesis results from the coordinated activities of different signaling pathways
controlling cell fate specification and morphogenesis. In vertebrate gastrulation, both Nodal …
controlling cell fate specification and morphogenesis. In vertebrate gastrulation, both Nodal …