Diabetic peripheral neuropathy: current perspective and future directions

R Singh, L Kishore, N Kaur - Pharmacological research, 2014 - Elsevier
Diabetic neuropathy is a heterogeneous group of disorders with extremely complex
pathophysiology and affects both somatic and autonomic components of the nervous …

Neuroinflammation and oxidative stress in diabetic neuropathy: futuristic strategies based on these targets

R Sandireddy, VG Yerra, A Areti… - International journal …, 2014 - Wiley Online Library
In Diabetes, the chronic hyperglycemia and associated complications affecting peripheral
nerves are one of the most commonly occurring microvascular complications with an overall …

Melatonin modulates neuroinflammation and oxidative stress in experimental diabetic neuropathy: effects on NF‐κB and Nrf2 cascades

G Negi, A Kumar, SS Sharma - Journal of pineal research, 2011 - Wiley Online Library
Melatonin exhibits an array of biological activities, including antioxidant and anti‐
inflammatory actions. Diabetic neuropathy is one of the complications of diabetes with a …

Treatment of diabetic peripheral neuropathy with engineered mesenchymal stromal cell-derived exosomes enriched with microRNA-146a provide amplified …

B Fan, M Chopp, ZG Zhang, XS Liu - Experimental neurology, 2021 - Elsevier
Diabetic peripheral neuropathy (DPN) is one of the most prevalent chronic complications of
diabetes mellitus with no effective treatment. We recently demonstrated that mesenchymal …

[HTML][HTML] Melatonin: new insights on its therapeutic properties in diabetic complications

MH Pourhanifeh, A Hosseinzadeh… - Diabetology & metabolic …, 2020 - Springer
Diabetes and diabetic complications are considered as leading causes of both morbidity
and mortality in the world. Unfortunately, routine medical treatments used for affected …

Diabetes mellitus and melatonin: Where are we?

R Patel, N Parmar, SP Palit, N Rathwa… - Biochimie, 2022 - Elsevier
Diabetes mellitus (DM) and diabetes-related complications are amongst the leading causes
of mortality worldwide. The international diabetes federation (IDF) has estimated 592 million …

Melatonin prevents mitochondrial dysfunction and promotes neuroprotection by inducing autophagy during oxaliplatin‐evoked peripheral neuropathy

A Areti, P Komirishetty, M Akuthota… - Journal of pineal …, 2017 - Wiley Online Library
Oxaliplatin, an organoplatinum compound, is used in the treatment of colorectal cancer, but
its clinical use can be limited due to the development of peripheral neuropathy. Whilst …

Nrf2 and NF-κB modulation by sulforaphane counteracts multiple manifestations of diabetic neuropathy in rats and high glucose-induced changes

G Negi, A Kumar, SS Sharma - Current neurovascular …, 2011 - ingentaconnect.com
High glucose driven reactive oxygen intermediates production and inflammatory damage
are recognized contributors of nerve dysfunction and subsequent damage in diabetic …

NF-κB inhibitory action of resveratrol: a probable mechanism of neuroprotection in experimental diabetic neuropathy

A Kumar, SS Sharma - Biochemical and biophysical research …, 2010 - Elsevier
Resveratrol has shown array of biological actions, and is under clinical development for
various disease conditions. The etiology of diabetic neuropathy revolves around oxidative …

Melatonin ameliorates low‐grade inflammation and oxidative stress in young Zucker diabetic fatty rats

A Agil, RJ Reiter, A Jiménez‐Aranda… - Journal of pineal …, 2013 - Wiley Online Library
The aim of this study was to investigate the effects of melatonin on low‐grade inflammation
and oxidative stress in young male Zucker diabetic fatty (ZDF) rats, an experimental model of …