Amplification-free CRISPR/Cas detection technology: challenges, strategies, and perspectives

H Li, Y Xie, F Chen, H Bai, L Xiu, X Zhou… - Chemical Society …, 2023 - pubs.rsc.org
Rapid and accurate molecular diagnosis is a prerequisite for precision medicine, food
safety, and environmental monitoring. The clustered regularly interspaced short palindromic …

Principles and applications of nucleic acid strand displacement reactions

FC Simmel, B Yurke, HR Singh - Chemical reviews, 2019 - ACS Publications
Dynamic DNA nanotechnology, a subfield of DNA nanotechnology, is concerned with the
study and application of nucleic acid strand-displacement reactions. Strand-displacement …

A CRISPR-Cas autocatalysis-driven feedback amplification network for supersensitive DNA diagnostics

K Shi, S Xie, R Tian, S Wang, Q Lu, D Gao, C Lei… - Science …, 2021 - science.org
Artificial nucleic acid circuits with precisely controllable dynamic and function have shown
great promise in biosensing, but their utility in molecular diagnostics is still restrained by the …

Programmable materials and the nature of the DNA bond

MR Jones, NC Seeman, CA Mirkin - Spherical Nucleic Acids, 2020 - api.taylorfrancis.com
A grand challenge in the fields of chemistry and materials science is the ability to construct f
the plac or a giv ement of en application. each component in or materials with absolute …

Electron-catalysed molecular recognition

Y Jiao, Y Qiu, L Zhang, WG Liu, H Mao, H Chen… - Nature, 2022 - nature.com
Molecular recognition,,–and supramolecular assembly,,–cover a broad spectrum,–of non-
covalently orchestrated phenomena between molecules. Catalysis of such processes …

[HTML][HTML] Research advances in the detection of miRNA

J Ye, M Xu, X Tian, S Cai, S Zeng - Journal of pharmaceutical analysis, 2019 - Elsevier
MicroRNAs (miRNAs) are a family of endogenous, small (approximately 22 nucleotides in
length), noncoding, functional RNAs. With the development of molecular biology, the …

Materials learning from life: concepts for active, adaptive and autonomous molecular systems

R Merindol, A Walther - Chemical Society Reviews, 2017 - pubs.rsc.org
Bioinspired out-of-equilibrium systems will set the scene for the next generation of molecular
materials with active, adaptive, autonomous, emergent and intelligent behavior. Indeed life …

DNA-based communication in populations of synthetic protocells

A Joesaar, S Yang, B Bögels, A van der Linden… - Nature …, 2019 - nature.com
Developing molecular communication platforms based on orthogonal communication
channels is a crucial step towards engineering artificial multicellular systems. Here, we …

Photocleavable Ortho-Nitrobenzyl-Protected DNA Architectures and Their Applications

MP O'Hagan, Z Duan, F Huang, S Laps, J Dong… - Chemical …, 2023 - ACS Publications
This review article introduces mechanistic aspects and applications of photochemically
deprotected ortho-nitrobenzyl (ONB)-functionalized nucleic acids and their impact on …

DNA nanotechnology from the test tube to the cell

YJ Chen, B Groves, RA Muscat, G Seelig - Nature nanotechnology, 2015 - nature.com
Abstract The programmability of Watson–Crick base pairing, combined with a decrease in
the cost of synthesis, has made DNA a widely used material for the assembly of molecular …